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Pressure BioSciences, Inc. (PBIO)

Pressure BioSciences, Inc. concentrates on the development, marketing, and sale of proprietary laboratory instrumentation and associated consumables based on Pressure Cycling Technology (PCT). PCT is a patented, enabling technology platform with multiple applications in the life sciences sample preparation market. PCT uses cycles of hydrostatic pressure between ambient and ultra-high levels to control bio-molecular interactions. So far, the company has installed over 250 PCT systems in approximately 160 sites around the world. Pressure BioSciences is based in South Easton, Massachusetts.

The company is focusing its efforts on the development and sale of PCT-enhanced sample preparation systems (instruments and consumables) for mass spectrometry, biomarker discovery, bio-therapeutics characterization, vaccine development, soil and plant biology, forensics, histology, and counter-bioterror applications. Its primary application development and sales efforts are in the biomarker discovery and forensics areas.

The PCT Sample Preparation System (PCT SPS) allows for the safe, fast, and reproducible extraction of DNA, RNA, small molecules, and proteins from a wide assortment of cells and tissues, especially those considered ‘hard-to-lyse’. The PCT SPS employs a Barocycler NEP3220, in tandem with PULSE™ Tubes.

Pressure BioSciences’ products include Barocycler Instruments, Shredders, PULSE Tubes (PT), PCT MicroTubes and PCT MicroCaps, PCT µPestle System, The Barozyme™ HT48, and also Kits & Reagents. In addition, the company is an authorized distributor of Constant Systems Ltd. products in the United States, Mexico, and Canada.

The Barozyme HT48 is a first-in-class, high throughput, PCT-based instrument. It can process up to 48 samples simultaneously using the company's proprietary BaroFlex 8-well, single-use processing strips. Collectively, the new Barozyme HT48 instrument and BaroFlex 8-well processing strips make up the Barozyme HT48 High-throughput System (the Barozyme HT48 System).

Pressure BioSciences announced this past February the receipt of the first purchase order for the company’s new Barozyme HT48 High-throughput System. Furthermore, it announced the receipt of a request for a quotation for the possible purchase of a second Barozyme HT48 System. This request came from an existing European customer.

Recently, Pressure BioSciences announced it entered into a Collaboration Agreement with Southern University at New Orleans (SUNO) to center on improving and extending the applications of Pressure BioSciences’ innovative and patented pressure cycling technology (PCT) platform for the detection of DNA in forensic samples. The program will be under the direction of Dr. Pam Marshall, Interim Director, Forensic Science Program and Assistant Professor, Department of Natural Sciences at SUNO.




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