Daily Stock List
Crocodile Gold Corp. (CRK.TO)
We are reporting on Crocodile Gold Corp. (CRK.TO), here at the QualityStocks Daily Newsletter.
Listed on the Toronto Stock Exchange, Crocodile Gold Corp. is a gold mining company with headquarters in Toronto, Ontario. The Company has three operating mines in Australia and a significant and prospective land package in the Northern Territory and the State of Victoria. Crocodile Gold is currently mining at the Fosterville and Stawell mines in the State of Victoria. In the Northern Territory, they continue to develop their Cosmo underground mine.
Crocodile Gold has an extensive exploration program in place in the Northern Territory. The Company is exploring on a number of key properties on their expansive land package. Their primary focus is on the Cosmo Mine, the Union Reefs, Pine Creek and Maud Creek project areas. In the State of Victoria, they have exploration programs in place designed to expand the resource base of each mine property.
At Crocodile Gold's Northern Territory properties, the Company has 3.175 million ounces of NI 43-101 reported Measured and Indicated mineral resources and 2.14 million ounces of Inferred mineral resources. These resources are inclusive of mineral reserves.
At the State of Victoria properties, Crocodile Gold has an additional 1.216 million ounces of NI 43-101 reported measured and indicated mineral resources (15.26 million tonnes at an average grade of 2.48 g/t gold) and 0.622 million ounces of inferred mineral resources (6.0 million tonnes at an average grade of 3.22 g/t gold). These resource estimates are exclusive of mineral reserves which total 0.472 million ounces.
Today, Crocodile Gold announced results of a Preliminary Economic Assessment (PEA) for the Big Hill Enhanced Development Project located at the Company's Stawell Gold Mine property. The Company has taken the first steps in the permitting process for the Project with the submission of an Environmental Effect Statement (EES) referral document to the State of Victoria, Australia.
Economic highlights include a Net Present Value of A$40.0M using a gold price of A$1,400/ounces and a discount rate of 10 percent; production of 2.3 million tonnes at an average grade of 1.65g/t Au, recovering more than 108,000 ounces of gold, and a project duration of four to five years, including a planned rehabilitation program. Highlights also include a stripping ratio of 3.2 to 1; an upfront capital requirement of A$17MM, and the creation of 80-100 jobs for the Stawell Region.
Crocodile Gold Corp. (CRK.TO), closed Thursday's trading session at $0.35, up 4.48%, on 321,525 volume. The stock's 52-week low/high is $0.29/$0.60.
Temex Resources Corp. (TME.V)
Streetwise Reports reported previously on Temex Resources Corp. (TME.V), and today we are highlighting the Company, here at the QualityStocks Daily Newsletter.
Temex Resources Corp. is an exploration company focusing on their portfolio of precious metals properties in northeastern Ontario. This region is a world class mining district. The Company is exploring their Timmins Whitney Property (60 percent), in partnership with Goldcorp (40 percent), and also exploring their Juby Gold Project. Temex Resources has their corporate headquarters in Toronto, Ontario. They list on the TSX Venture Exchange.
Temex Resources has rapidly growing resources and quality infrastructure. The Company has an Ontario, NI 43-101 Resource Base. The Whitney Gold Project is an advanced gold project. It includes 4 km of the prolific Timmins gold trend. The Whitney property contains a number of near-surface gold targets. These include the Upper Broulan Reef Zone, C Zone, and Q Zone.
The Whitney Property has NI 43-101 compliant resources on the Upper Hallnor of 3.0 million tonnes at a grade of 2.44 g/t gold for 234,300 ounces of gold in the Measured category, 8.8 million tonnes at a grade of 1.97 g/t gold for 555,900 ounces of gold in the Indicated category, and 4.1 million tonnes at a grade of 1.82 g/t gold for 241,000 ounces of gold in the Inferred category. These are all at a cut-off grade of 0.30 g/t gold.
The Juby Main Zone has NI 43-101 compliant resources of 22.3 million tonnes at a grade of 1.30 g/t gold for 934,645 ounces of gold in the Indicated category and 28.2 million tonnes at a grade of 1.00 g/t gold for 905,621 ounces of gold in the Inferred category, both at a cut-off grade of 0.40 g/t gold.
This month, Temex Resources announced that they received the first set of assays from their drilling program at their Juby Gold Project near Matachewan, Ontario. Results for drill holes GL12-09 to GL12-14 on the Golden Lake portion of the project continue to quickly expand the Juby Main Zone gold zone to depth and demonstrate excellent continuity for 1 kilometer along strike to the west, intersect new zones of high-grade gold mineralization, and confirm previous drilling results in this new area of the project. All six holes reported this month successfully intersected gold mineralization that is typical of the Juby Main Zone (JMZ) over extensive and increasing widths.
Temex Resources Corp. (TME.V), closed Thursday's trading session at $0.255, down 3.77%, on 242,500 volume. The stock's 52-week low/high is $0.10/$0.36.
Clean Enviro Tech Corp. (SPOWD)
OTCPicks reported yesterday on Clean Enviro Tech Corp. (SPOWD) and today we are highlighting the Company here at the QualityStocks Daily Newsletter.
Clean Enviro Tech Corp. engages in the development of Stand Alone Residential Solar Concentrating Electric Power Generation Systems for homeowners. In addition, Clean Enviro Tech is developing lithium ion rechargeable batteries for power production. Lithium ion batteries are rechargeable and composed of cathode, anode, separator and electrolytes.
The Company formerly went by the name Sky Power Solutions Corp. They changed their name to Clean Enviro Tech Corp. in this month of January 2013. Clean Enviro Tech Corp. has their headquarters in Las Vegas, Nevada. The Company's shares trade on the OTC Bulletin Board.
Clean Enviro Tech is developing safe rechargeable battery systems for diverse applications ranging from portable electronics to onboard energy storage in EVs. The Company is pioneering a superlattice cathode material for use in lithium ion rechargeable batteries. Their objective is to improve continually their proprietary semi-solid synthesis process for the development of lithium ion rechargeable battery technologies to meet the growing needs for a less expensive, high-energy density, extended life and fast recharging battery while keeping safety as a priority.
Clean Enviro Tech's Solar Concentrating Electric Power Generation System is an extremely efficient photovoltaic solar power generation unit. This system is able to produce greater than 2 Kilowatts (kw) of electric power with zero emissions. Sunlight is the only fuel used including built-in heat capture to provide hot water to users. The Company designed and developed this system as they anticipate that the North American Power Grid will not be able to support the recharging of anticipated sales of totally electric vehicles and other electric needs in the coming years.
In December 2012, the Company announced that further to a PR dated December 3, 2012, they have finalized and both parties have signed the Agreement for an R&D and distributing license in Canada. They confirmed the distribution license would be for the territory of Canada where federal and provincial governments have implemented generous Initiatives.
Clean Enviro Tech Corp. (SPOWD), closed Thursday's trading session at $0.121, down 71.79%, on 700 volume with 2 trades. The average volume for the last 60 days is 9,539 and the stock's 52-week low/high is $0.0041/$4.835.
Rambler Metals & Mining PLC (RAB.V)
We are highlighting Rambler Metals & Mining PLC (RAB.V) today, here at the QualityStocks Daily Newsletter.
Rambler Metals & Mining PLC is a junior mining company that has 100 percent ownership of the Ming Copper-Gold Mine in Baie Verte, Newfoundland and Labrador (NL), Canada. The Ming mine is in a mining district with excellent infrastructure including roads, fresh water, hydro electricity, and access to a working port. The Company's strategy is to identify opportunities for acquisition, exploration and development of base metal deposits in countries with perceived low political risk.
Rambler Metals & Mining has their corporate headquarters in Sutton, the United Kingdom (UK). Rambler Metals & Mining Canada Ltd. has their office in Baie Verte, NL. The Company's shares trade on the TSX Venture Exchange. Rambler's Directors have experience in the complete cycle of base metal mining exploration, mine development, fund raising, metals and concentrate trading and commercial negotiations with the shipping and smelting industries.
The town of Baie Verte is 17 km away from the Ming Copper-Gold Mine. The mine is mainly an underground volcanic massive sulphide style copper deposit with anomalously high gold grades. Rambler has transitioned the project from exploration, permitting, construction, development, commissioning, production ramp up and now production. On November 1, 2012, the Company confirmed that the Ming Mine was officially in commercial production. Today, all mineralization remains open in multiple directions. The deposit has not been cut-off at depth.
Rambler Metals & Mining has their operational gold hydrometallurgical mill, Nugget Pond. This mill is approximately 40 km from the Ming Mine. The Company has expanded the mill so that it is capable of handling massive sulphides from the Ming Mine to produce a copper concentrate with gold and silver as by-products.
Through using the hydrometallurgical facility, in tandem with the concentrator, Rambler anticipates increased gold recovery as well as recovering any free gold. The tailings from the copper floatation circuit will undergo processing in the second quarter of fiscal 2013, in the gold hydrometallurgical mill, before being discharged into the tailings pond increasing gold recovery from 66 percent to 85 percent as shown in laboratory tests.
Rambler Metals & Mining PLC (RAB.V), closed Thursday's trading session at $0.55, up 1.85%, on 16,000 volume. The stock's 52-week low/high is $0.33/$0.65.
Tonix Pharmaceuticals Holding Corp. (TNXP)
FeedBlitz and plrinvest reported earlier on Tonix Pharmaceuticals Holding Corp. (TNXP), and we choose to report on the Company today, here at the QualityStocks Daily Newsletter.
Tonix Pharmaceuticals Holding Corp. is a specialty pharmaceutical company. The Company is developing therapies for challenging disorders of the central nervous system (CNS), including fibromyalgia syndrome (FM) and post-traumatic stress disorder (PTSD). Tonix focuses on conditions characterized by significant unmet medical need, inadequate existing treatment options, and high dissatisfaction among both patients and physicians. Tonix Pharmaceuticals' shares trade on the OTC Bulletin Board. The Company has their corporate headquarters in New York, New York.
Fibromyalgia Syndrome (FM) is a common and complex central nervous system (CNS) condition. It is characterized by chronic diffuse musculoskeletal pain, increased pain sensitivity at multiple tender points, fatigue, abnormal pain processing, disturbed sleep and often, psychological stress. Post-traumatic stress disorder (PTSD) is an anxiety disorder. It can develop from seeing or experiencing a terrifying event or ordeal in which there was the threat or actual occurrence of grave physical harm.
Tonix Pharmaceuticals reformulates approved pharmaceutical active ingredients to design products with optimal safety, efficacy and predictability. Tonix' lead product candidate, TNX-102 SL, is a novel under-the-tongue tablet formulation of cyclobenzaprine, the active ingredient in two U.S. Food and Drug Administration (FDA)-approved muscle relaxants. An Investigational New Drug application (IND) for TNX-102 SL for FM is active. The expectation is that this candidate will enter a pivotal program in FM in early 2013. The Company is also exploring the utility of TNX-102 SL in a new bedtime treatment paradigm for PTSD. The Company has held a pre-IND meeting with the FDA to discuss PTSD. They expect to file a second IND for this indication in early 2013.
In December 2012, Tonix Pharmaceuticals announced that they raised $1.0 million in gross proceeds from a private placement offering with Technology Partners. Together with the closing of a prior tranche of the private placement of $2.4 million announced December 5, 2012, this constitutes the final closing of a $3.4 million private placement. Technology Partners is a leading life science venture capital firm.
Tonix Pharmaceuticals' intention is to use the proceeds from the Offering to further the development of TNX-102 sublingual tablet (TNX-102 SL), a proprietary formulation of cyclobenzaprine (CBP) for bedtime use. They also intend to use the proceeds for general working capital.
Tonix Pharmaceuticals Holding Corp. (TNXP), closed Thursday's trading session at $0.50, even for the day. The average volume for the last 60 days is 138 and the stock's 52-week low/high is $0.25/$2.06.
Redhawk Resources, Inc. (RHWKF)
Today we are reporting on Redhawk Resources, Inc. (RHWKF), here at the QualityStocks Daily Newsletter.
Redhawk Resources, Inc. is a resource exploration and development company that lists on the OTCQX International and on the Toronto Stock Exchange under the symbol RDK.TO. The Company is primarily focusing on the accelerated development of their advanced stage Copper Creek copper-molybdenum project in San Manuel, Arizona. The Copper Creek Property is 75 road miles northeast of Tucson and 15 miles northeast of San Manuel. It is in an area well situated concerning existing general and copper mining infrastructure. The original 7 square mile property was increased in 2011-2012 by the addition of a further 22 square miles of contiguous property. Redhawk Resources has their headquarters in Vancouver, British Columbia.
Copper Creek hosts multiple Breccia and Porphyry Copper Deposits. Both deposit types include current copper/molybdenum resources compliant to Canadian National Instrument 43-101 standards. Molybdenum is present in different amounts in the Breccia and Porphyry Copper deposits. The expectation is that it will provide substantial credits to both deposit types. In addition, Gold and Silver are present in both deposit types and are expected to provide credits during mining.
Earlier this month, Redhawk Resources announced that they completed the consolidation of the Copper Creek mining district by entering into agreements to acquire over 1.4 square miles of additional patented properties contiguous to Copper Creek. Staking has been completed on the Cooper Creek North property expansion. This brings the contiguous Copper Creek district land package to approximately 35 square miles. Furthermore, Redhawk has also successfully completed an independent Quality Assurance and Quality Control (QAQC) review conducted by Dr. Jeffrey Jaacks, an industry accepted QAQC specialist.
The Copper Creek property is in the prolific southwest U.S. porphyry copper belt at the projected intersection of a major northwest belt of porphyry copper deposits or mines (Ray, Miami/Globe, Superior/Resolution, Johnson Camp) and a major east-northeast belt of porphyry deposits (San Manuel/Kalamazoo, Silver Bell, Lakeshore, Safford, Morenci). The property is within sight of the former BHP Kalamazoo/San Manuel copper smelter and mine and within 30 miles of an existing operating copper mill and smelter.
Redhawk Resources, Inc. (RHWKF), closed Thursday's trading session at $0.56, up 1.82%, on 55,983 volume with 12 trades. The average volume for the last 60 days is 25,310 and the stock's 52-week low/high is $0.344/$0.794.
Texas Gulf Energy, Inc. (TXGE)
Stock Twiter, Investor News Source, Actual Gains, Penny Dreamers, Bullseyestox.com, and PennyStockRumors.net reported earlier on Texas Gulf Energy, Inc. (TXGE), and today we are reporting on the Company, here at the QualityStocks Daily Newsletter.
Founded in 2003, Texas Gulf Energy, Inc. is a construction, maintenance, turnaround, and management-services company. They provide their services to Refining, Chemical Production, Industrial Gas Production, Midstream Operations, Mining & Minerals, Oil & Gas, Power Generation, Power Transmission, and Pulp & Paper Production industries. Texas Gulf Energy provides craftspeople, architects, and engineers in the energy construction sector in the United States. They offer turnkey as well as specialty construction services.
The Company was formerly known as Global NuTech, Inc. They changed their corporate name to Texas Gulf Energy, Inc. in March of 2012. Texas Gulf Energy lists on the OTC Bulletin Board. The Company is based in LaPorte, Texas.
The Company's services include full-service construction, program/project management, turnaround management, turnaround execution, and maintenance. Their services additionally include electrical and instrumentation, pipe and vessel fabrication, craft labor resources, as well as upstream services and production.
Their subsidiary service companies include Fishbone Solutions Inc. – project leadership, including management and project controls, services and personnel; TGE Industrial Services – full-service construction, turnarounds and maintenance; TGE Electrical & Instrumentation – heavy industrial E&I construction, and Texas Gulf Oil & Gas, Inc. – oilfield services and production. Subsidiaries also include Texas Gulf Fabricators – premier pipe and vessel fabrication; International Plant Services, LLC – domestic and international project resources, as well as Texas Gulf International – international construction, maintenance and turnarounds.
The main services of their Construction Services segment include Capital Projects, Revamps, Turnarounds, Grassroots Construction, and Project & Construction Management. They also include Constructability Services, Procurement, Project Controls, Direct-Hire Construction, and Resources & Staffing, Sub Contracts Management, and Specialty Welding.
Their Program/Project management offerings include Defining Scope of Work - Detailed Estimating/ (WBS), Planning/Scheduling - Primavera P3 – P6, SCOPE Software (Proprietary Planning Software), and Project Schedule and Budget Compliance. Offerings additionally include Budget and Duration Benchmarking, Cost Management Systems/Professionals, Project Discipline Engineers, as well as Project Management.
Texas Gulf Energy, Inc. (TXGE), closed Thursday's trading session at $0.14, up 40.00%, on 26,500 volume with 3 trades. The average volume for the last 60 days is 2,060 and the stock's 52-week low/high is $0.10/$0.14.
Dynamic Energy Alliance Corp. (DEAC)
UndiscoveredEquities, FeedBlitz, Investor Insights, and SmallCapVoice reported earlier on Dynamic Energy Alliance Corp. (DEAC), and we highlight the Company today, here at the QualityStocks Daily Newsletter.
Based in Dallas, Texas, Dynamic Energy Alliance Corp. is a development stage energy and recycling company. The Company was formed with the objective of creating environmentally sound and necessary "Waste-to-Profit Solutions". The Company will work to achieve this by identifying, combining and maximizing an assortment of existing, proven and innovative "Renewable Energy" technologies to create state-of-the-art production facilities called "Dynamic Energy Campuses™".
The Company focuses on identifying, combining and enhancing existing technologies with proprietary recoverable production and finishing processes to produce synthetic oil, carbon black, gas, and carbon steel from waste feedstock. The expectation is that this process will be accomplished with limited residual waste product and substantial reductions in greenhouse gases in comparison to traditional processing.
To maximize this opportunity, Dynamic Energy Alliance has developed a scalable, commercial development strategy to build the aforementioned "Energy Campuses" with low operational costs and long-term, recurring revenues. The Company’s Pyrol-Black Energy Campuses will be in areas where tires are currently being handled. Each Pyrol-Black Energy Campus is expected to directly employ approximately 40 full-time permanent employees. Buildings will be used for each process to convert scrap tires to energy. They will be fully equipped with the appropriate tank storage for product distribution, and comfortably accommodate the employees to manage the energy operations effectively.
The Pyrol-Black Energy Campus consists of three independently operating technologies referred to as Pyrol-A, Carbon-B and Petrol-C. Dynamic Energy Alliance will use these technologies to convert scrap tires primarily into 4 high-value, saleable products. These include pyrolysis oil, carbon black, a high BTU (butane like) gas and steel wire.
In October 2012, Dynamic Energy Alliance announced that they initiated the first phase (prototype phase) of a four-phase operating plan to validate and commercialize patent pending technologies that extract high value organic compounds from waste tires.
The Company is progressing on a timetable in which the prototype phase started in Q4 2012, followed by Phase Two (TKF scale-up phase) starting Q1 2013. After completion of the first two phases, they will be in a position to implement the TKF pilot phase, anticipated to commence Q1 2014 or sooner. In this phase, they will build a pilot (demonstrator) plant with an estimated 50 gallon-per-day capacity. Phase Four will be a fully operational and modular 25 ton-per-day state-of-the-art pyrolysis plant, which the Company plans to construct and operate while additionally focusing on the syndication of their processes to interested third parties.
Dynamic Energy Alliance Corp. (DEAC), closed Thursday's trading session at $0.055, up 37.50%, on 15,980 volume with 4 trades. The average volume for the last 60 days is 12,076 and the stock's 52-week low/high is $0.011/$0.30.
Bergamo Acquisition Corp. (BGMO)
The QualityStocks Daily Newsletter would like to spotlight Bergamo Acquisition Corp. (BGMO). Today, Bergamo Acquisition Corp. closed trading at $0.05, even with yesterday's close, on 198,060 volume with 9 trades. The stock’s average daily volume over the past 60 days is 288,075, and its 52-week low/high is $0.01/$0.07.
Bergamo Acquisition Corp., which was up 18.00% to $0.059 in after-market trading, offered markets an update today regarding the engagement of full-service public accounting firm L.L. Bradford for the purposes of verifying and authenticating documents supporting the two most recent $500M tranches deposited into accounts of the company's European subsidiary as part of an investment agreement with National Wealth International. President and CEO of BGMO, Hillard Herzog, personally verified the vetting of these documents by the firm, as detailed in the letter of confirmation posted on the OTC Markets website (www.otcmarkets.com/stock/BGMO/filings). This move by BGMO to have the corporate CPA examine everything should clear up any doubt that the company is able to move directly ahead with its investment program.
Bergamo Acquisition Corp. (BGMO) is a global investor targeting a diversified portfolio of large corporate and middle-market companies for sole acquisition and co-investment alongside other sophisticated investors such as private equity funds, hedge funds, investment banks, and other institutions. The company has engaged investments in financial instruments and companies worldwide.
Alternative energy is a key focus of the company. Bergamo Acquisition has developed solar generators for cell phone towers, solar generators for home and industry applications, and solar operated tube well water pumping systems to meet the vast needs of emerging markets. The company’s turnkey solutions help developers, utilities, water districts, power plant owners, and industrial customers diversify their existing generation portfolio.
Bergamo Acquisition executes energy projects from concept through completion, offering design, construction management, and facility maintenance services. Together with pre-designed and packaged Balance of Plant and standardized Power Plant Control Modules, the company enables rapid project commissioning and provides an optimum balance between capital cost, plant performance, and operational and maintenance expenses.
The company’s technical team has been working with government officials, manufactures, and importers in Asia, Africa, and the Middle East to introduce its state-of-the-art technology. Investable funds are already in place to pursue investment opportunities in these and other countries. Bergamo Acquisition relies on its extensive network within the global institutional investment and banking industries to source the best opportunities. Disclaimer
Bergamo Acquisition Corp. Company Blog
Bergamo Acquisition Corp. News:
Bergamo Acquisition Corp. Provides Authenticated Documentation to Confirm Bank Deposits
L.L. Bradford Letter Confirms Funding Reported by Bergamo Acquisition Corp.
Bergamo Acquisition Corp. Signs Investment Agreement
Advaxis, Inc. (ADXS)
The QualityStocks Daily Newsletter would like to spotlight Advaxis, Inc. (ADXS). Today, Advaxis, Inc. closed trading at $0.072, up 4.35%, on 2,351,494 volume with 141 trades. The stock’s average daily volume over the past 60 days is 3,477,597, and its 52-week low/high is $0.0275/$0.165.
Advaxis, Inc. (ADXS) is a clinical-stage biotechnology company developing the next-generation of immunotherapies for cancer and infectious diseases. The company’s immunotherapies are based on a novel platform technology that uses live, bio-engineered bacteria to secrete an antigen/adjuvant fusion protein that redirects the powerful immune response all human beings have to fight off cancer and disease.
The company has more than fifteen distinct constructs in various stages of development, all of which are involved in strategic collaborations with recognized centers of excellence such as the National Cancer Institute, Cancer Research – UK, the Wistar Institute, the University of Pennsylvania, the University of British Columbia, the Karolinska Institutet, and others.
Advaxis’ lead construct, ADXS-HPV, is currently in Phase 2 clinical development for recurrent/refractory and advanced cervical cancer, CIN 2/3, and HPV caused head and neck cancers. This important construct was recognized as the Best Therapeutic Vaccine (approved or in development) at the 5th Annual Vaccine Industry Excellence (ViE) Awards by the vaccine industry and the journal Expert Reviews of Vaccines.
The estimated global market for immunotherapies is projected to exceed $37.2B by 2012, with cancer vaccines forecast to grow into an $8B market. Protected by 77 issued and pending patents, Advaxis is extremely well positioned to capitalize on the burgeoning opportunities in the healthcare sector as it advances the development of next-generation treatments for today’s most challenging diseases. Disclaimer
Advaxis, Inc. Company Blog
Advaxis, Inc. News:
Advaxis to Present at the 6th Annual OneMedForum
Advaxis Appoints Daniel J. O'Connor to Senior Vice President, Chief Legal and Business Development Officer
Advaxis Receives Preliminary Approval for Sale of Losses from State of NJ Economic Development Authority
VistaGen Therapeutics, Inc. (VSTA)
The QualityStocks Daily Newsletter would like to spotlight VistaGen Therapeutics, Inc. (VSTA). Today, VistaGen Therapeutics, Inc. closed trading at $0.80, up 0.63%, on 4,000 volume with 4 trades. The stock’s average daily volume over the past 60 days is 1,723, and its 52-week low/high is $0.06/$3.10.
VistaGen Therapeutics, Inc. (VSTA) is a biotechnology company applying stem cell technology for drug rescue and cell therapy. Drug rescue combines human stem cell technology with modern medicinal chemistry to generate new chemical variants ("drug rescue variants") of once-promising drug candidates that have been discontinued during late-stage preclinical development due to heart or liver safety concerns. VistaGen also focuses on cell therapy, or regenerative medicine, which includes repairing, replacing or restoring damaged tissues or organs.
VistaGen's versatile stem cell technology platform, Human Clinical Trials in a Test Tube™, has been developed to provide clinically relevant predictions of potential heart and liver toxicity of promising new drug candidates long before they are ever tested on humans.
By more closely approximating human biology than conventional animal studies and other nonclinical techniques and technologies currently used in drug development, VistaGen's human stem cell-based bioassay systems can improve the predictability of the drug development cycle and lower the cost of new drug research and development by identifying product failures earlier in the cost curve. According to the Food and Drug Administration even only a ten percent improvement in predicting failure before clinical trials could save $100 million in development costs, which savings ultimately could be passed on to patients.
Using mature human heart cells produced from stem cells, VistaGen has developed and internally validated CardioSafe 3D™, a novel three-dimensional (3D) bioassay system for predicting the in vivo cardiac effects of new drug candidates before they are tested in humans. VistaGen is now focused on using CardioSafe 3D™ to generate up to two new, safer small molecule drug rescue variants every twelve to eighteen months. VistaGen anticipates that these drug rescue variants will be modified versions of once-promising new drug candidates that have been discontinued by pharmaceutical companies and academic research institutions because of heart toxicity concerns, despite substantial prior investment and positive efficacy data demonstrating their potential therapeutic and commercial benefits. In most cases, VistaGen plans to license or sell its new, safer drug rescue variants in strategic partnering arrangements with global pharmaceutical companies, arrangements providing VistaGen with both near term and downstream milestone payments and economic participation rights but without future development cost obligations.
AV-101, VistaGen's lead small molecule prodrug candidate has successfully completed Phase I clinical development in the U.S. for treatment of neuropathic pain, a serious and chronic condition affecting millions of people worldwide, depression, and other neurological diseases and conditions. To date, the U.S. National Institutes of Health (NIH) has awarded VistaGen over $8.75 million for development of AV-101. Management anticipates strategically out-licensing AV-101 to a development and marketing partner in 2013.
Neuropathic pain affects approximately 1.8 million people in the U.S. alone. Although the current active AV-101 IND is for the treatment of neuropathic pain, VistaGen's development plan and regulatory strategy for AV-101 has been designed to allow its Phase 1 safety studies to support Phase 2 development for depression, epilepsy, Huntington's Disease and Parkinson's disease, indications for which there is now supporting preclinical efficacy data. To date, VistaGen has been awarded over $8.5 million from the U.S. National Institutes of Health (NIH) for development of AV-101.
VistaGen is also developing LiverSafe 3D™, a novel predictive liver toxicity and drug metabolism bioassay system for drug rescue applications. In parallel with drug rescue activities, the Company is funding early-stage nonclinical studies focused on potential cell therapy applications of its Human Clinical Trials in a Test Tube™ platform. Disclaimer
VistaGen Therapeutics, Inc. Company Blog
VistaGen Therapeutics, Inc. News:
Vistagen Therapeutics Successfully Completes Final Phase 1 Safety Study of AV-101
VistaGen Therapeutics to Present at Noble Financial Capital Markets Ninth Annual Equity Conference
VistaGen Therapeutics Becomes Member of Centre for Commercialization of Regenerative Medicine Consortium
Cardium Therapeutics, Inc. (CXM)
The QualityStocks Daily Newsletter would like to spotlight Cardium Therapeutics, Inc. (CXM). Today, Cardium Therapeutics, Inc. closed trading at $0.19 even for the day, on 100,684 volume with 83 trades. The stock’s average daily volume over the past 60 days is 198,135, and its 52-week low/high is $0.17/$0.399.
Cardium Therapeutics, Inc. (CXM) is a health sciences and regenerative medicine company focused on acquiring and strategically developing new and innovative products and businesses to address significant unmet medical needs. Comprised of large-market opportunities with definable pathways to commercialization, partnering, and other economic monetizations, Cardium's current portfolio includes the Tissue Repair Company, Cardium Biologics, and the company's in-house MedPodium Health Sciences healthy lifestyle product platform.
The company's lead commercial product Excellagen® topical gel for wound care management recently received FDA clearance for marketing and sale in the United States. In addition to plans to advance the product's commercialization in the U.S. and internationally via strategic partnerships, the company plans to develop new product extensions for additional wound healing applications and is working towards securing approval for marketing and sale in South Korea and through the CE Mark application process in the European Union.
Generx®, Cardium's lead clinical development product candidate, is a DNA-based angiogenic biologic designed to treat patients with myocardial ischemia due to coronary artery disease. Cardium recently initiated its Generx Phase 3 / registration study in Russia. Consistent with its capital-efficient business model, Cardium is also actively evaluating new technologies and business opportunities. The company utilizes its team's skills in late-stage product development to bridge the critical gap between promising new technologies and product opportunities that are ready for commercialization.
Cardium is dedicated to building on its core products and product candidates to continually create new opportunities for greater success. Leveraging the advantages of its capital-efficient, asset-based business strategy, the company provides a diversified and more balanced portfolio of risk/return opportunities with the chief objective of providing long-term shareholder value. Disclaimer
Cardium Therapeutics, Inc. Company Blog
Cardium Therapeutics, Inc. News:
Cardium Announces Presentation at The 2013 Cell & Gene Therapy Forum
Cardium To Present At Biotech Showcase 2013 Investment Conference And Report On New Cardium Initiatives
Cardium Announces Sales and Distribution Agreement With Academy Medical to Promote Excellagen Clinical Adoption by U.S. Government Medical Providers
A recent article by Ryan McBride in biotech industry newsletter FierceBiotech (http://dtg.fm/i12W) highlights a major transition that needs to occur in the pharmaceutical industry.
The article points to a speech by Ken Kaitin, director of the Tufts Center for the Study of Drug Development, suggesting that drug development companies need to fix broken areas of development that are costing them billions of dollars from unnecessary procedures in clinical trials. Kaitin’s group expects pharma to replace traditional trial-and-error testing methods with newer approaches, such as biomarkers, modeling, and simulation, all in an effort to reduce failures and associated costs, costs which payers are increasingly reluctant to accept.
It’s exactly the issue that is being addressed by VistaGen Therapeutics’ proprietary stem cell technologies. VistaGen is a California-based biotechnology company applying its human pluripotent stem cell technology for drug rescue applications, including predictive toxicology and drug metabolism screening. The company intends to use its proprietary technology to discover, rescue, and develop novel drug candidates for a wide range of diseases.
The company’s platform, Human Clinical Trials in a Test Tube, is based on the differentiation of human pluripotent stem cells into multiple types of mature human heart and liver cells which can then be used to provide clinically relevant predictions of potential toxicity. Determination of toxicity at these early stages, far earlier than standard clinical trials, means that drug candidates have a chance of being modified for a successful outcome, saving tremendous amounts of money.
Many otherwise promising drug candidates have been shelved due to toxicity issues that surfaced well into the development and introduction process, representing major losses for drug companies. It suggests a growing recognition of the incredible value offered by technologies such as those VistaGen represents.
For additional information, visit www.VistaGen.com
Gryphon Gold, who sold roughly 1.58k ounces of gold (32 tons of loaded carbon) during fiscal 2012 via their Borealis Oxide Heap Leach Operation in Nevada, reported entry today into an agreement package with Waterton Global Value L.P. and one of its subsidiaries to expand this extremely productive operation via a joint venture.
Waterton will obtain a 60% ownership interest in GYPH’s operating subsidiary, Borealis Mining Company, via the agreement, which will see Waterton converting the lion’s share currently outstanding under the Senior Credit Facility ($17M, or roughly two-thirds). This brings the amount in the Senior Credit Facility down to only $8M, shearing monthly debt payments (starting Jan 31) from $1.4M to an easily manageable $0.4M and creating a robust capital structure from which to engage production expansion efforts at Borealis.
This is great news for GYPH, which was lucky to find and quickly get a new boiler in at their ADR plant (adsoption, desorption, and recovery) after the old one failed recently (reported Jan 15). The ADR facility, able to strip four tons of carbon per day, was completed back in May of 2012, and thanks to a quick turnaround with the boiler, GYPH has managed to sell 3,280 gold equivalent ounces in Q1 of FY13. This JV will help up the output at Borealis a great deal, thanks not only to the capital support enabling additional crushing capacity expansion and hauling equipment purchases, but because Waterton brings a “wealth of technical expertise and successful gold mining experience” to the table, according to CEO and Interim CFO of GYPH, James T. O’Neil Jr.
O’Neil assured markets that this JV would strengthen the Borealis operation considerably and lead to an increased overall mining/production effort. In conjunction with this important move to shore up debt and form a new tactical front via the JV, Gryphon Gold and Waterton have entered into an operational and financial obligation arrangement with several key stipulations:
• Gryphon shall pay $4M compensation to the JV to settle extant obligations incurred prior to the deal, as well as their share (40%) of the contemplated initial $4M capital contribution
• Waterton will advance $5.6M to Gryphon ($3M already in) to cover initial capital contributions to the JV (to be repaid with escalating interest by July 31)
• Borealis ownership percentage will determine each parties required obligation for ongoing capital contributions, with all determinations going through the Borealis board of managers
• Dilution of ownership will be the consequence of failure to meet financial obligations by either party, in addition to which Gryphon, if failing to meet monthly Senior Credit Facility obligations, shall incur the same dilution penalty as per terms of the associated Credit Agreement
Portfolio Manager at Waterton, Cheryl Brandon, summed it all up nicely noting that a combination of near-term output upgrade initiatives being undertaken at Borealis and Waterton’s added financial/logistical muscle should jack up both recovery rate and mine life parameters. A solid, solid move for GYPH, who can now focus confidently on material aspects of the operation, impelled by these new dynamics and better able to wring out improved returns from the Borealis site for their shareholders.
For more information on Gryphon Gold, visit www.GryphonGold.com
JA Solar Holdings recently announced the completion of the delivery of 9.5 MW of PV modules to the Volkswagen Solar Park. The installation contains 33,600 high-performance multi-crystalline silicon PV modules across 33 acres of land next to the Volkswagen manufacturing plant in Chattanooga, Tennessee. The modules have been supplied exclusively by JA Solar.
Based in Shanghai, China, JA Solar is focused on manufacturing solar power products intended for residential, commercial, and utility-scale power generation. JA Solar produces solar modules which it distributes under its own brand, and also manufactures products for other solar manufacturers. The company also has facilities in Shanghai, as well as Hebei, Jiangsu, and Anhui provinces.
The solar park, which is the largest such park in Tennessee, was constructed by Phoenix Solar for Silicon Ranch Corp. The park will sell the electricity to Volkswagen under a 20-year power purchase agreement, and is expected to produce 13,100,000 kWh of electricity annually. Volkswagen Group of America Chattanooga Operation LLC hosted a “power up” dedication ceremony on January 23.
Jonathan Pickering, president of JA Solar, said, “The United States is one of the fastest growing markets in the global solar industry and we are proud to have JA Solar modules powering this landmark Volkswagen solar installation. JA Solar is committed to providing high-quality, high-performance, and high-reliability solar modules to our customers and we are pleased to have been selected by Phoenix Solar for this project. Phoenix Solar has an outstanding reputation as a global leader in the design and construction of solar systems, and we’ve enjoyed a very close partnership as both companies grow in the United States.”
“We are delighted to have worked together with JA Solar on the Volkswagen Solar Park installation,” said Dr. Murray Cameron, CEO and president of U.S.-based Phoenix Solar Inc. “JA Solar’s high-quality products and professional technical and customer services were key to the success of the project and we look forward to collaborating again in the future.”
For more information, visit www.jasolar.com
WidePoint announced that Mr. John Atkinson will be joining the company as its new Executive Vice President of Sales and Marketing. Atkinson will bring over 28 years of experience to WidePoint, a leading provider of cloud-based telecommunications services and cyber security solutions.
Of his new role, Atkinson remarked, “I look forward to being part of the executive team at WidePoint and bringing my expertise and relationships into a marketplace that is poised for wide adoption and growth. In particular, I’m excited about the strategic charge of implementing a suite of integrated secured mobility solutions offered at the Enterprise level.”
Having spent almost 30 years in the Information Technology sector, Atkinson possesses a strong background in developing, building, and deploying international sales and marketing strategies, teams, and channels. His resume includes time spent at companies such as Lenovo, WinMagic, IdentiPhi, Gieseche & Devrient, Gemplus, Samsung, and Hitachi. In his new role, Atkinson will oversee the sales and marketing management of WidePoint’s overall product and services offerings.
“John has an excellent record in developing and executing sales and marketing strategies and brings both broad-based experience and relevant expertise to WidePoint at this juncture, as we work to broaden our solutions and customer reach,” remarked Steve Komar, WidePoint’s CEO. “He will be an important, driving asset in further strengthening WidePoint’s leadership position in the Telecom Management and Identity Assurance and Management space as we continue to work at converging our solutions and delivering enterprise-wide integrated solutions to our customers and prospects, while expanding our market presence and position.”
WidePoint, with Atkinson’s presence, is now be in a position to continue the building and deploying of a robust sales and marketing infrastructure in 2013. The company plans to broaden its solutions and reach from the federal sector to state and local municipalities, in addition to finding commercial market opportunities (both in the U.S. and abroad) to meet the needs of its multi-national customer base.
For more information, visit www.widepoint.com
Today's Top 3
Epic Stock Picks
The QualityStocks Public Company Sponsor News