Kraig Biocraft Laboratories, Inc. (KBLB)

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Postby QualityStocks » Fri Feb 06, 2009 2:22 pm

The Status of Kraig Biocraft Laboratories, Inc. (KBLB.OB) Technology and Expected Time Frames

Kraig Biocraft Laboratories has their focus on developing high performance polymers and technical fibers. The company is utilizing their proprietary genetic engineering technology to develop and produce polymers and protein-based materials, including spider silk, which may have numerous commercial and consumer applications.

The company possesses coded gene sequences that relate to spider silk production and is currently working on injecting this material into silkworm eggs. The team at the University of Notre Dame, led by Dr. Fraser, has recently been strengthened to further refine the microinjection process as well as increase the number of microinjections preformed.

In most recent news, the company excitedly announced that the scientific team has achieved the activation of fluorescent marker gene sequences that were incorporated into spider silk DNA packets by the researchers. The team has successfully inserted the DNA packets into silkworms, which are now visibly emitting florescence. This achievement is a huge step forward for Kraig Labs. The fact that these proteins are markers establishes that the DNA packets have been successfully transferred.

Kraig Biocraft has a particular focus within the biotech industry where FDA approval of its resulting technologies and products is not required. This means that once the company has produced the desired transgenic silkworm, it can immediately move into production, licensing agreements or a direct sale of the technology or of the entire company.

After achieving its goal of creating a line of silkworms capable of producing spider silk fibers in commercial quantities, the company will most likely decide one of two things. One choice would be selling the entire company or licensing the technology to one of the larger technical textile market participants. An alternative would be to pursue bulk sales of fibers produced by the transgenic silkworms. Because this would require significant additional financing and a greater amount of time to attain profits, an outright acquisition or a licensing agreement is more likely.
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future

Postby protostars » Mon Feb 09, 2009 9:27 am

Remember that, as they continue to develop these proprietary genetic engineering technologies, and with no lengthy FDA approval required, they could sell or license fairly quickly :!:
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Postby mrsfelix06 » Mon Feb 09, 2009 1:03 pm

Even with no lengthly fda approval, would there be any other approvals needed to be met.
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Postby QualityStocks » Mon Feb 09, 2009 1:10 pm

Kraig Biocraft Laboratories Inc (KBLB.OB): Investing in People Who have Proven Themselves

Both existing and potential investors of Kraig Biocraft Laboratories Inc (KBLB.OB) should understand that they have one of the most pioneering and accomplished minds in the field of genetic engineering working in their corner. This member of Kraig’s Scientific Advisory Board, Dr. Malcolm Fraser, presides over the University of Notre Dame’s transgenic-based laboratory which has currently been focusing on developing “spider silk” polymers.

Since Kraig and Notre Dame have partnered in a collaboration agreement, essentially exchanging funding for both R&D data and intellectual property rights, Kraig is uniquely positioned to benefit from the work conducted under Dr. Fraser at Notre Dame. Consequently, the company’s stock performance will be heavily tied to Dr. Fraser’s breakthroughs in the laboratory.

Considering Kraig’s track record, investors should feel at ease with the notion that his work can single handedly affect Kraig’s stock price. Shortly after the turn of the century, Dr. Fraser patented what has become one of the most utilized methods directed to insert genes in insects. Since this US Patent 6,218,185 titled Piggybac transposon-based genetic transformation system for insects was issued, over 190 pending or patented applications have come through the United States Patent and Trademark Office.

A recent study also compared this Piggybac transposon to three other transposons commonly used for “jumping genes” into insects, and subsequently found the Piggybac transposon performed five to ten times better. As a result of this technical breakthrough pioneered by Dr. Fraser, universities across the globe have already paid over $300,000 to his group in licensing fees in order to use this Piggybac metholodology in their laboratories.

Now that Kraig has joined forces with Dr. Fraser, research and development has focused on incorporating this Piggybac technique in silkworms such that high performance spider silk polymers can be spun. The rapid progress in this area of spider silk has already been highlighted by the filing of at least two provisional patent applications under the assignee of the University of Notre Dame. While these applications have not been made public and have yet to be examined, this is a very welcoming sign of good things to come under the direction of Dr. Fraser and Kraig Biocraft Laboratories Inc.
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Postby mrsfelix06 » Mon Feb 09, 2009 2:29 pm

It will be interesting to see how this piggybac metholodolgy will come out. looks like a bit of money was invested in the metholodogly, its great to hear that another force has joined.
Also what applications
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Postby QualityStocks » Tue Feb 10, 2009 9:55 am

Kraig Biocraft Laboratories, Inc. (KBLB.OB) - Innovation in Genetic Engineering

Kraig Biocraft operates in a multi-billion dollar world market that has been growing by as much as 30 percent each year since the mid-Seventies. This market is Genetic Engineering. While some aspects of this relatively new science have become controversial due to many moral and legal implications, the work being done at Kraig Biocraft would be applauded by even the shrewdest skeptics. The end result of the research and development taking place at Kraig could very well improve our lives, without causing the same sort of harm associated with many areas of the field.

Human beings have been aware of the astonishing strength of certain types of spider silk for generations, yet have never been able to harness it for practical use. Scientists realized that while the silk itself could be reproduced artificially, its true strength was derived from the spinnerets (silk glands) of the spiders which produced it naturally. This realization led to a fundamental roadblock with respect to mass-production for commercial use which has stumped the scientific community for decades. Spiders are cannibalistic, rendering the formation of a collective large enough to produce adequate quantities of silk practically impossible.

The scientists at Kraig Biocraft believe that they have found the solution to this technical issue: The Silkworm. By inserting the genetic “code” for silk used by spiders into silkworms, which boast spider-like spinnerets, they believe it is possible to create a medium in which large amounts of this astronomically useful substance can be economically produced. The ramifications of their success will be far-reaching indeed. The possible areas of application for “packaged” spider silk include, but are not limited to: textiles, industrial netting, automotive (such as seatbelts and airbags), ropes and cables with unprecedented strength, as well as several architectural, military, aeronautic, and everyday uses.

The company holds proprietary genetic engineering technologies that will affect the successful commercialization of the finished product. It seems only a matter of time before spider silk replaces high-tensile steel as the preferred substance of engineers everywhere. If and when that happens, Kraig Biocraft Laboratories will likely be at the forefront of a revolution in the production of high-performance polymers that could change the world.
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Postby QualityStocks » Tue Feb 10, 2009 9:59 am

Kraig Biocraft Laboratories, Inc. (KBLB.OB) Makes Substantial Progress in the Labs; Achieves New Company Record Ahead of Schedule

Today, Kraig Biocraft announced that Dr. Fraser’s research team has successfully made 5,000 genetic transfers in a single week using the newly designed DNA insertion packets. The Company anticipates having preliminary test results back on these five thousand genetic insertions within the next 45 days.

“Every DNA packet insertion has the potential to create a new recombinant fiber with commercial applications. The achievement of 5,000 such insertions in a single week is something that the Company would not have dreamed of in 2008,” CEO Kim K. Thompson enthusiastically stated. “At the same time, Dr. Fraser is reporting a large increase in the team’s observation of the occurrence of transient expression shortly after the gene transfers are preformed.” The research team believes this is a strong indication of the viability of the genetic transfers.

“More importantly,” added Mr. Thompson, “the research team is now performing these gene transfers in large numbers on a regular basis. That means that there will be a nearly continuous group of gene transfers benign tested. Every single gene insertion has the potential to create a new commercially viable spider silk polymer. With this number of gene insertions the odds of our developing a viable polymer are increasing exponentially.”

According to the press release, Kraig Biocraft believes these dramatic increases in productivity are the direct result of Mr. Thompson’s successful efforts to reorganize the research team in 2008.
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Postby QualityStocks » Wed Feb 11, 2009 5:12 pm

Kraig Biocraft Laboratories, Inc. (KBLB.OB) - Increased Lab Productivity Draws Attention from Investors

As a result of yesterday’s announcement, which heralded a recent milestone achievement of Kraig Labs scientists, several promotional firms have initiated coverage of the company. In addition, a rising buzz in online investment communities’ message boards and chatrooms has been observed.

Kraig’s lab specialists have successfully accomplished a previously unheard-of number of genetic insertions using newly designed DNA “packets”. In a single week, they successfully transferred five thousand packets containing the genetic code for silk found in spiders to silkworm recipients. This increased productivity essentially means that the odds of Kraig Labs successfully developing a commercially feasible spider silk polymer have been greatly increased.

Following the release of the good news yesterday, respected firms like Stockguru.com swiftly took the opportunity to lend support. This, along with continual coverage by QualityStocks, helped propel Kraig Labs to its second highest daily trading volume of the new year.

It would arguably be unwise to allow Kraig Biocraft Laboratories to slip from one’s radar, especially during this exciting time of advancement in the company’s efforts to solve one of nature’s many riddles on a genetic level. Attacking the long-standing obstacles of spider silk production on a grand scale has the research team at Kraig Labs knocking on the door of a significant scientific breakthrough.
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Postby protostars » Fri Feb 13, 2009 10:01 am

It's about time this place got some recognition! SS may be a household word someday, but it's still under the radar right now.
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Postby QualityStocks » Tue Feb 17, 2009 12:16 pm

Kraig Biocraft Laboratories, Inc. (KBLB.OB) is Led By a Group of Visionary Researchers

Kraig Biocraft Labs, a biotech research firm with its sights set on producing spider silk in commercial quantities, is ever-advancing toward its goal with the help of an extremely talented group of scientists. With the success of their endeavors rapidly materializing as an eventuality, as opposed to a possibility, the Kraig Labs researchers are nearing the culmination of more than 30 years of combined experience with complex protein polymers derived from the silk of a spider.

The lineup begins with Dr. Malcolm Fraser, graduate of Ohio State University, whose work in developing a genetic expression system now plays an instrumental role in the industrial production of organic molecules. Dr. Fraser is also the co-inventor of the “piggyBac” gene-splicing method, an achievement which led to his being named a fellow of the American Association for the Advancement of Science.

Aiding Dr. Fraser is Dr. Randy Lewis, a biochemist with accreditation from UC San Diego, and holder of numerous patents relating to the field of spider silk polymer production. Dr. Lewis has, quite impressively, been dedicated to the pursuit of spider silk research since 1990, when he contributed to the first of more than a dozen scientific papers on the subject.

Rounding out the group is Dr. Donald Jarvis, who obtained his Ph.D in Virology at Baylor College of Medicine. Like Dr. Fraser, Dr. Jarvis holds several patents in the field of molecular biology, and genetic engineering. Though his work with spider silk did not begin until after 2000, Dr. Jarvis has been a leading authority in biochemistry for more than 20 years.

These individuals, along with others, are working tirelessly to effect the development of a method by which spider silk may be commercially produced. The technical possibilities with respect to hypothetical uses of the substance following their success are nearly limitless. Kraig Biocraft Laboratories is approaching this goal by leaps and bounds, thanks to the vision and ingenuity of these talented scientists.
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Postby QualityStocks » Tue Feb 17, 2009 12:21 pm

Kraig Biocraft Laboratories, Inc. (KBLB.OB) to Discuss Proposed Forward Stock Split

Today, Kraig Biocraft Laboratories announced that its Board of Directors will be contemplating a proposed forward stock split of the company’s common stock. The meeting has been scheduled to take place after the close of the markets on Wednesday, February 18.

Kraig Biocraft Laboratories, Inc. (KBLB), a biotechnology company, has their focus on developing high performance polymers and technical fibers. The company is utilizing their proprietary genetic engineering technology to develop and produce polymers and protein-based materials, including Spider silk, which may have numerous commercial and consumer applications.
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Postby QualityStocks » Wed Feb 18, 2009 3:26 pm

Kraig Biocraft Laboratories, Inc. (KBLB.OB) Buyout Potential

It is no mystery that Kraig Biocraft Laboratories is a research and development company. They do not have the infrastructure to immediately compete against the biggest players in the technical textiles market. They do not need to focus on supply chain management or building a large sales and marketing team. This is simply not their goal.

Investors or potential investors should not be alarmed by this “lack of infrastructure” if you will. The long-term performance of one’s investment in this company is based on its response to two fundamental questions: 1) Can Kraig Biocraft harness its spider silk technology into a package that can be readily used in commercial applications, and 2) Does Kraig Biocraft have the intellectual property rights behind its technology?

From recent statements delivered within the past year from CEO Kim Thompson, it appears that Kraig is very much on the verge of fulfilling both of the questions above. Once they are met, Kraig will be seen as an attractive buyout to those companies having the established infrastructures capable of delivering Kraig’s technologies in commercial applications. DuPont and Honeywell would be the first two major players that come to mind.

Amid the economic downturn, the number of mergers and acquisitions within the biotech fields has remained consistent and extremely beneficial to the company taken over. Look at other buyout offers within the biotech field during the past two years:

• At $1.72 per share, synthetic fuels and fertilizer technology company Rentech Inc was proposed to be bought out at $2.70 per share by Sherwood Investments Overseas Ltd (November 2007) - Rentech shares rose more than 32 percent on the news that day
• When GlaxoSmithKline PLC proposed to buy Genelabs Technologies Inc. for $1.30 per share, the stock price of Genelabs rose 430% (October 2008)

Overall, it appears that Kraig’s stock price may move moderately from here on findings in the laboratory or based on the progress with current or new patent filings. The huge jump will take place when a takeover is announced. Whether this news takes place in a year or in two years, the investment will be well worth the wait considering the potential gains that can be made in that one day.
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Not quite as big as one might think

Postby rose » Thu Feb 19, 2009 10:40 am

Although a buyout would make life quite a bit easier for the investor, the technical fabrics marketplace is largely one of smaller and mid-range companies. Yes, the Duponts of the world are there and supply much of the materials but there is an opportunity for a buyer, rather then the scientists engaged in development, to take the company into a world of endless possibilities without a complete sellout to the big boys.




QualityStocks wrote:Kraig Biocraft Laboratories, Inc. (KBLB.OB) Buyout Potential

It is no mystery that Kraig Biocraft Laboratories is a research and development company. They do not have the infrastructure to immediately compete against the biggest players in the technical textiles market. They do not need to focus on supply chain management or building a large sales and marketing team. This is simply not their goal.

Investors or potential investors should not be alarmed by this “lack of infrastructure” if you will. The long-term performance of one’s investment in this company is based on its response to two fundamental questions: 1) Can Kraig Biocraft harness its spider silk technology into a package that can be readily used in commercial applications, and 2) Does Kraig Biocraft have the intellectual property rights behind its technology?

From recent statements delivered within the past year from CEO Kim Thompson, it appears that Kraig is very much on the verge of fulfilling both of the questions above. Once they are met, Kraig will be seen as an attractive buyout to those companies having the established infrastructures capable of delivering Kraig’s technologies in commercial applications. DuPont and Honeywell would be the first two major players that come to mind.

Amid the economic downturn, the number of mergers and acquisitions within the biotech fields has remained consistent and extremely beneficial to the company taken over. Look at other buyout offers within the biotech field during the past two years:

• At $1.72 per share, synthetic fuels and fertilizer technology company Rentech Inc was proposed to be bought out at $2.70 per share by Sherwood Investments Overseas Ltd (November 2007) - Rentech shares rose more than 32 percent on the news that day
• When GlaxoSmithKline PLC proposed to buy Genelabs Technologies Inc. for $1.30 per share, the stock price of Genelabs rose 430% (October 2008)

Overall, it appears that Kraig’s stock price may move moderately from here on findings in the laboratory or based on the progress with current or new patent filings. The huge jump will take place when a takeover is announced. Whether this news takes place in a year or in two years, the investment will be well worth the wait considering the potential gains that can be made in that one day.
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Difficult Choice

Postby protostars » Thu Feb 19, 2009 10:47 am

In the end, I think the biggest money will likely do the biggest talking. It will be tough to get everyone involved to turn down immediate cash for future prospects. Especially since the big companies have rows of patent attorneys that can turn an apparently solid patent into a piece of swiss cheese.
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Postby mrsfelix06 » Thu Feb 19, 2009 10:59 am

I think that Kraig can put together a package that will be able to be used. Development just dosn't happen overnight, and some companies have been trying to develop products, and solutions for things withought ever fullfilling them. It sounds like technology is underway, and that any opsticals or questions will hopefully not go unanswered.
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patents

Postby protostars » Thu Feb 19, 2009 11:03 am

And let's hope that their patents are as puncture-proof as their threads.
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Postby mrsfelix06 » Thu Feb 19, 2009 11:12 am

good point to bring up. Has there been anyword on anykind of patent comming out?
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Re: patents

Postby rose » Fri Feb 20, 2009 10:11 am

yes to all but terminology and function wise; yarns not threads when in use ans vibration dispersion not puncture- yarns don't actually puncture - the threat goes between the yarns and disperse the energy of the threat.Just thought I'd pass it along for clarity. Don't mean to be a kia

protostars wrote:And let's hope that their patents are as puncture-proof as their threads.
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Postby mrsfelix06 » Fri Feb 20, 2009 2:28 pm

Thanks for the clarification!
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Postby QualityStocks » Fri Feb 20, 2009 5:38 pm

Review of Kraig Biocraft Laboratories, Inc. (KBLB.OB) Recent Progress in the Labs

In the past four weeks, Kraig Biocraft Laboratories has had two significant announcements. Exactly a month ago, the company announced that its scientific team succeeded in activating fluorescent marker gene sequences which the researchers incorporated into spider silk DNA packets. This means that the DNA insertion packets are working and that Kraig Biocraft has succeeded in obtaining chromosomal insertion and expression.

CEO Kim K. Thompson had this to say after the success, “Not only are the DNA packets incorporating themselves into the silkworm chromosome as expected, the silkworms are actually producing the fluorescent proteins as they are instructed to do by the genetic coding in the spider silk insertion packets… This is a dramatic shift forward in the Company’s spider silk and high performance polymer development program.”

In more recent news, the company announced that it has accomplished five thousand genetic transfers in a single week using the newly designed DNA insertion packets. The achievement exceeded the company’s wildest expectations in 2008, and more importantly, the research team is now performing these gene transfers in large numbers on a regular basis. With this number of gene insertions, the odds of the company developing a viable polymer is increasing exponentially.
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