PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

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PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Fri Jan 05, 2018 12:51 pm

PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE:18H), headquartered in Vancouver, British Columbia, Canada, is a health sciences company dedicated to researching and developing innovative options for preventive and curative therapies utilizing organic and Nature Identical™ products. The company is strategically staking out select positions in the medically acute areas of diabetes and obesity, pain management, neurological disorders and cancer.

PreveCeutical Medical Inc. had its beginnings in 2009 when Stephen Van Deventer, a seasoned businessman and venture capitalist, and Kimberly Van Deventer, a successful entrepreneur, met and formed a business partnership. The duo created Cornerstone Global Partners, a venture capital and business development company, and became involved in numerous ventures including building companies such as Aurora Cannabis Inc. Taking their interest in the health and wellness market further, the pair began researching how nature and science can work together to benefit health-conscious consumers. Coining and trademarking the word “PreveCeutical” – a combination of the words “preventive” and “pharmaceutical” – was a precursor to the company’s formation and incorporation in October 2015.

The company’s first product was developed in the Dominican Republic and is now marketed and distributed worldwide by PreveCeutical. It is a Caribbean Blue Scorpion venom product sold under the trade name CELLB9®. This product is an oral dilute solution infused with select peptides sourced exclusively from the blue scorpion (Rhopalurus princeps) found only in Caribbean nations. The active potentiated ingredients in CELLB9, which have been used in over 40 countries for over a decade, appear to support health at a deep, cellular level. PreveCeutical’s research team is using proprietary chemistry to generate Nature Identical™ peptides derived from natural compounds found in Caribbean Blue Scorpion venom with the goal of eventually treating, regulating and preventing cancer progression. Peptides are also being used to target an array of disease indications including metabolic disorders, pain management, cancers, cardiovascular and infectious diseases.

PreveCeutical is developing the first nose-to-brain delivery system of cannabinoids (CBDs) with a novel process that prepares insoluble drug-containing nano-micelles and successfully incorporating them into a proprietary sol-gels application, essentially creating a targeted drug delivery vehicle. Intended for use via a nasal spray, this unique formulation rapidly gels upon contact with mucosal tissue, which paves the way for direct nose-to-brain delivery. This novel application eliminates first pass metabolism (stomach, intestines, liver), potentially improving bioavailability and delivering extended time release formulations that may alleviate side effects of higher dosage therapeutics. This CBD-based patented formula is projected to be deployed in selected markets with licensed medical marijuana companies within 18 months.

PreveCeutical is working with four leading Australian research centers to develop a curative therapy for diabetes and obesity. This four-year program involves engineering a novel approach that selectively targets the gene that encodes for the protein PTP-1B, which is implicated and over-expressed in both type-2 diabetes and obesity. PreveCeutical’s gene-silencing technology would effectively “turn off” the genetic signal which leads to the over-production of this key protein molecule, bringing it back down to safe, normalized levels, and prevent the body from storing excessive fat. Diabetes kills one person every six seconds, with more than $800 billion spent globally on the disease.

Another exciting joint venture, established with Sports 1 Marketing, will focus on the therapeutic potential in the peptides and proteins connected to the Caribbean Blue Scorpion venom to potentially treat mild brain injury concussions. Developing a therapeutic product geared towards athletes who suffer from concussions could help alleviate suffering experienced by those who are affected by head trauma.

PreveCeutical Medical’s science and research team is led by Dr. Harendra (Harry) Parekh, Ph.D., who is based at the University of Queensland’s (UQ) Pharmacy Australia Centre of Excellence (PACE), and Dr. Makarand Jawadekar, Ph.D., whose 28 years of R&D experience with Pfizer Inc., is applicable in his role as chief science officer. Research collaborators include Dr. Rakesh Veedu, an emerging expert internationally in the field of molecular medicine, and Professor Grant Ramm, who is currently head of a leading medical research institute located in Brisbane, Australia.

PreveCeutical Medical is partnering with leading industry experts and companies in its quest to be a leader in the preventive health sciences sector. Its Research and Development partnership with UniQuest, the main commercialization company for the University of Queensland, provides PreveCeutical with the rights to all intellectual property arising from projects created under the agreement. PreveCeutical Medical Inc.’s management team brings an extensive portfolio of research experience, product development, deep corporate strategy and capital markets leadership to the company’s core.
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Fri Jan 05, 2018 6:13 pm

PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) is “One to Watch”

- Developing Nature Identical™ peptides derived from Caribbean Blue Scorpion venom to treat, regulate and prevent cancer progression
- Global market for cancer treatments projected to reach $161.3 billion by 2021
- Unique Sol-gel nose-to-brain CBD delivery platform under development to provide clinical relief of various physical disorders
- Global neuropathic pain market estimated at $8.3 billion by 2024
- Proof of concept already demonstrated for dual-gene therapy for type 2 diabetes and obesity
- Global expenditure for diabetes market in 2016 reached $825 billion

PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE:18H), headquartered in Vancouver, British Columbia, Canada, is a health sciences company dedicated to researching and developing innovative options for preventive and curative therapies utilizing organic and Nature Identical™ products. The company is strategically staking out select positions in the medically acute areas of diabetes and obesity, pain management, neurological disorders and cancer.

PreveCeutical Medical Inc. had its beginnings in 2009 when Stephen Van Deventer, a seasoned businessman and venture capitalist, and Kimberly Van Deventer, a successful entrepreneur, met and formed a business partnership. The duo created Cornerstone Global Partners, a venture capital and business development company, and became involved in numerous ventures including building companies such as Aurora Cannabis Inc. Taking their interest in the health and wellness market further, the pair began researching how nature and science can work together to benefit health-conscious consumers. Coining and trademarking the word “PreveCeutical” – a combination of the words “preventive” and “pharmaceutical” – was a precursor to the company’s formation and incorporation in October 2015.

The company’s first product was developed in the Dominican Republic and is now marketed and distributed worldwide by PreveCeutical. It is a Caribbean Blue Scorpion venom product sold under the trade name CELLB9®. This product is an oral dilute solution infused with select peptides sourced exclusively from the blue scorpion (Rhopalurus princeps) found only in Caribbean nations. The active potentiated ingredients in CELLB9, which have been used in over 40 countries for over a decade, appear to support health at a deep, cellular level. PreveCeutical’s research team is using proprietary chemistry to generate Nature Identical™ peptides derived from natural compounds found in Caribbean Blue Scorpion venom with the goal of eventually treating, regulating and preventing cancer progression. Peptides are also being used to target an array of disease indications including metabolic disorders, pain management, cancers, cardiovascular and infectious diseases.

PreveCeutical is developing the first nose-to-brain delivery system of cannabinoids (CBDs) with a novel process that prepares insoluble drug-containing nano-micelles and successfully incorporating them into a proprietary sol-gels application, essentially creating a targeted drug delivery vehicle. Intended for use via a nasal spray, this unique formulation rapidly gels upon contact with mucosal tissue, which paves the way for direct nose-to-brain delivery. This novel application eliminates first pass metabolism (stomach, intestines, liver), potentially improving bioavailability and delivering extended time release formulations that may alleviate side effects of higher dosage therapeutics. This CBD-based patented formula is projected to be deployed in selected markets with licensed medical marijuana companies within 18 months.

PreveCeutical is working with four leading Australian research centers to develop a curative therapy for diabetes and obesity. This four-year program involves engineering a novel approach that selectively targets the gene that encodes for the protein PTP-1B, which is implicated and over-expressed in both type-2 diabetes and obesity. PreveCeutical’s gene-silencing technology would effectively “turn off” the genetic signal which leads to the over-production of this key protein molecule, bringing it back down to safe, normalized levels, and prevent the body from storing excessive fat. Diabetes kills one person every six seconds, with more than $800 billion spent globally on the disease.

Another exciting joint venture, established with Sports 1 Marketing, will focus on the therapeutic potential in the peptides and proteins connected to the Caribbean Blue Scorpion venom to potentially treat mild brain injury concussions. Developing a therapeutic product geared towards athletes who suffer from concussions could help alleviate suffering experienced by those who are affected by head trauma.

PreveCeutical Medical’s science and research team is led by Dr. Harendra (Harry) Parekh, Ph.D., who is based at the University of Queensland’s (UQ) Pharmacy Australia Centre of Excellence (PACE), and Dr. Makarand Jawadekar, Ph.D., whose 28 years of R&D experience with Pfizer Inc., is applicable in his role as chief science officer. Research collaborators include Dr. Rakesh Veedu, an emerging expert internationally in the field of molecular medicine, and Professor Grant Ramm, who is currently head of a leading medical research institute located in Brisbane, Australia.

PreveCeutical Medical is partnering with leading industry experts and companies in its quest to be a leader in the preventive health sciences sector. Its Research and Development partnership with UniQuest, the main commercialization company for the University of Queensland, provides PreveCeutical with the rights to all intellectual property arising from projects created under the agreement. PreveCeutical Medical Inc.’s management team brings an extensive portfolio of research experience, product development, deep corporate strategy and capital markets leadership to the company’s core.

For more information, visit the company’s website at www.PreveCeutical.com
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Mon Jan 08, 2018 6:21 pm

NetworkNewsBreaks – PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Utilizes Caribbean Blue Scorpion Venom in Proprietary CELLB9

Health sciences company PreveCeutical Medical (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) is developing Nature Identical™ peptides derived from Caribbean Blue Scorpion venom to treat, regulate and prevent cancer progression. An article discussing this reads: “The company’s first product was developed in the Dominican Republic and is now marketed and distributed worldwide by PreveCeutical. It is a Caribbean Blue Scorpion venom product sold under the trade name CELLB9®. This product is an oral dilute solution infused with select peptides sourced exclusively from the blue scorpion (Rhopalurus princeps) found only in Caribbean nations. The active potentiated ingredients in CELLB9, which have been used in over 40 countries for over a decade, appear to support health at a deep, cellular level. PreveCeutical’s research team is using proprietary chemistry to generate Nature Identical™ peptides derived from natural compounds found in Caribbean Blue Scorpion venom with the goal of eventually treating, regulating and preventing cancer progression. Peptides are also being used to target an array of disease indications including metabolic disorders, pain management, cancers, cardiovascular and infectious diseases.”
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Fri Jan 12, 2018 9:26 pm

NetworkNewsBreaks – PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Receives Initial Coverage from Crystal Equity Research

On January 9, 2018, Crystal Equity Research published an initial report on PreveCeutical Medical (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (http://nnw.fm/aO8gG), a biomedical company with a focus on preventative health sciences. Among other highlights, the report noted the company’s recapitalization efforts to fund its development program, as well as the strategic mergers and distribution agreements to address additional markets, including the sports medicine market. The company’s initial product, CELLB9, is an innovative therapy based on blue scorpion venom. The sales from CELLB9 represent the company’s current revenue stream, which helps to balance out research and developmental spending.
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Fri Jan 19, 2018 6:56 pm

PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Combining Nature and Science to Make Life Better

- Company utilizing novel Caribbean blue scorpion venom therapy for immune system boost
- PreveCeutical seeks new ways to treat cancers, metabolic disorders, pain, infectious diseases and cardiovascular disease
- Partnership with University of Queensland researchers advances scientific scope of projects

In the modern health care industry, disease prevention has taken a commanding role as screenings and regularly scheduled physician visits aim to minimize costs that could otherwise spiral out of control once a chronic condition is established. However, the Centers for Disease Control and Prevention report an ongoing concern that Americans are using preventive services at about half the recommended rate (http://nnw.fm/b93YW). British Columbia-based PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) was founded on the principle that prevention is the best policy in health care and that nature and science may combine to provide an array of innovative, untapped solutions to otherwise unmet clinical needs.

PreveCeutical is taking a new look at ways to combat chronic health concerns such as diabetes and obesity, pain management, neurological disorders and cancer. PreveCeutical developed its CELLB9® oral dilute solution utilizing select peptides from the blue scorpion, which is found only in the Caribbean region. PreveCeutical’s “Nature Identical” research team is building on proprietary chemistry to produce controlled venom peptides that it hopes will be able to halt the progression of cancers, while also exploring the peptides’ potential in responding to other medical concerns related to metabolic disorders, pain, cardiovascular disease and infectious maladies.

During 2017, the company entered a partnership with UniQuest Pty Limited that directs UniQuest to conduct research programs at the University of Queensland in Australia on PreveCeutical’s behalf. The partnership identified development programs for four therapies.

One of those is aimed at assessing pain and inflammation models with the idea of developing non-addictive analgesics for moderate to severe pain. The three-phase research project was expected to last up to 24 months under the terms of the research and option agreement (http://nnw.fm/MdVB9) with the goal of identifying the scorpion peptides and a means of replicating them in a laboratory, rather than having to rely on milking the scorpions for their venom, then screening the peptides in various disease models of interest.

PreveCeutical is also developing a proprietary gel application, called Sol-gels, for delivering a CBD-based medical cannabis formulation directly to the brain. Sol-gels are taken via nasal (systemic) administration and rapidly gel upon contact with mucosal tissue, which paves the way for direct nose-to-brain delivery. This effectively bypasses the stomach and intestines – eliminating first-pass metabolism – and may dramatically improve bioavailability, even compared to nasal sprays and other newer delivery systems. Additionally, the gel stays in the nasal passages, slowly releasing the CBD while keeping it active for up to seven days. The ease of application and its long-lasting effects may be attractive for patients when compared to other delivery systems.

The company’s four-year program targeting diabetes and obesity seeks also to engineer a therapy that recognizes a gene common and overactive in the two ailments. The therapy would “silence” the gene — turning it off to prevent the overproduction of a protein molecule believed to play a role in the declines commonly associated with diabetes and obesity.

Successes in these endeavors would solidify PreveCeutical’s efforts to become recognized as a pioneer in preventative medicine and increased quality of life factors.

For more information, visit the company’s website at www.PreveCeutical.com
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Thu Jan 25, 2018 8:04 pm

NetworkNewsBreaks – PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Issues Update on Scorpion Venom Research Program

Health sciences company PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) this morning offered an update on its scorpion venom-derived peptide research and development program, which consists of identifying, extracting and sequencing peptides and proteins isolated from Caribbean blue scorpion venom. Per the update, the program is progressing on schedule through the first of its three distinct phases. As previously noted, PreveCeutical has successfully separated several target scorpion venom-derived peptides and proteins using both one-dimensional gel electrophoresis (“1DE”) and two-dimensional gel electrophoresis (“2DE”). Next, the company’s research team aims to sequence the extracted peptides and proteins in order to determine their respective amino acid fingerprints, progressing toward the ultimate goal of enabling the creation of Nature Identical™ peptides.
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Thu Jan 25, 2018 8:13 pm

NetworkNewsBreaks – PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Enhances Life by Uniting Nature and Science

An ongoing concern in North America, as reported by the Centers for Disease Control and Prevention, is that Americans are only taking advantage of preventive medical services about half as often as they should. Endeavoring to become a pioneer in preventative medicine, health science company PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) was founded on the belief that, in healthcare, prevention is the best policy, and that nature and science can unite to offer a range of innovative, untapped solutions to address unmet clinical needs. As quoted in a recent article: “PreveCeutical is taking a new look at ways to combat chronic health concerns such as diabetes and obesity, pain management, neurological disorders and cancer. PreveCeutical developed its CELLB9® oral dilute solution utilizing select peptides from the blue scorpion, which is found only in the Caribbean region. PreveCeutical’s “Nature Identical” research team is building on proprietary chemistry to produce controlled venom peptides that it hopes will be able to halt the progression of cancers, while also exploring the peptides’ potential in responding to other medical concerns related to metabolic disorders, pain, cardiovascular disease and infectious maladies.”
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Fri Jan 26, 2018 8:44 am

Fast-Growing Cannabis Industry Drives Biotech Research, Innovative Medical Therapy Development

NetworkNewsWire Editorial Coverage: The rapidly growing cannabis industry has spawned a range of diverse companies focusing on innovative technologies for cannabis cultivation, as well as the development of cannabis-based medical therapies for an array of diseases and ailments. The market has given rise to biotech companies with exciting advances in product formulation and delivery. At the cutting-edge of innovation, PreveCeutical Medical Inc. (OTCQB: PRVCF) (CSE: PREV) (FSE: 18H) (PRVCF Profile) has developed an innovative cannabidiol (CBD)-based nose-to-brain delivery system for the relief of a number of medical conditions. Another company, Lexaria Bioscience Corp. (OTC: LXRP) (LXRP Profile) has developed its own proprietary system for CBD-based therapy delivery. And with a market cap of over $3.6 billion, GW Pharmaceuticals plc (NASDAQ: GWPH) is an established giant in the cannabis biotech space developing plant-derived cannabinoid therapeutics. Canadian cultivator Canopy Growth Corp. (TSE: WEED) is an example of yet another company that could benefit from its therapeutic advances as the anticipated commercial availablity of pharmaceutical-grade cannabis products is met by greater demand.

The cannabis market is likely to surpass $31 billion by 2021, billowing from its value of $6.5 billion in 2016, according to a Brightfield Group report quoted by Forbes (http://nnw.fm/b75xW). A different report by investment bank Cowen & Co. estimates that the market will increase to $50 billion by 2026 (http://nnw.fm/wmv6C). This caliber of growth, to a large extent, is fueled by the increasing legalization of cannabis for medical and recreational use in Canada and in many states across the United States. As demand for cannabis-based medications grows, the market will become increasingly competitive, compelling companies to develop innovative therapies and delivery systems to gain more traction in the marketplace.

Diverse Portfolio Creates Multiple Market Opportunities

Headquartered in Vancouver, Canada, PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE:18H) started out in 2009 as a partnership between established businessman and venture capitalist Stephen Van Deventer, and entrepreneur Kimberley Van Deventer. The synergy of the pair’s respective aptitudes led to the creation of Cornerstone Global Partners, a venture capital and business development company.

Today, PreveCeutical is a life science company that researches and develops innovative solutions for preventative and curative therapies through a combination of organic and Nature Identical™ products. With the preventative healthcare technologies market expected to reach $432 billion by 2024 (http://nnw.fm/UF8u8), the company has made a strategic decision to focus on warding off illness in the medically acute areas of diabetes, obesity, pain management, neurological disorders and cancer.

By maintaining a diverse portfolio of novel compounds and products, PreveCeutical is able to compete in several niches of the health care industry, including immunity-boosting sciences and medicinal cannabis.

PreveCeutical has a product, CELLB9®, an oral dilute solution utilizing select peptides from the blue scorpion, found only in the Caribbean region. PreveCeutical’s “Nature Identical” research team is building on proprietary chemistry to produce controlled venom peptides that it hopes will be able to halt the progression of cancers, while also exploring the peptides’ potential in responding to other medical concerns related to pain management, metabolic disorders, cancers, cardiovascular conditions and infectious diseases.

PreveCeutical is currently in a joint venture with Sports 1 Marketing to focus on the therapeutic potential of the Natural Identical venom’s peptides and proteins to treat mild brain injury concussions in athletes.

The company is also currently working with four leading Australian research centers to develop a curative therapy for diabetes and obesity. This is a novel four-year program selectively targeting the gene that encodes for the protein PTP-1B, implicated and over-expressed in both Type-2 diabetes and obesity.

Globally, over $800 billion is spent on diabetes, with one person dying every six seconds from the disease (http://nnw.fm/2OqnS) in 2014, presenting to PreveCeutical significant market opportunity and the potential to alter the diabetes landscape.

Notably, PreveCeutical’s innovative gene-silencing technology would effectively disable the genetic signal that leads to over-production of PTP-1B. This would bring this protein down to safe, normalized levels that would prevent the body from storing excessive fat.

PreveCeutical’s Groundbreaking Sol-Gel Delivery System

PreveCeutical in November announced its approval from the Environmental Hazards Unit of the Queensland Government (the Australian state-level authority) to acquire, store and use high-quality dried cannabis plant extracts, paving the way for the company to advance its R&D program for the commercialization of a new system for administering the drug (http://nnw.fm/47wwI).

The company believes its Sol-gel platform will be the first FDA-approved, CBD-based nose-to-brain delivery system of its kind to provide relief for pain, inflammation, seizures and neurological disorders. PreveCeutical’s proprietary nasal formulations will be designed for use by both adults and children. The company expects to have this delivery platform fully tested, approved and primed for deployment to licensed medical cannabis companies in 2019.

PreveCeutical’s Sol-gels are taken via nasal administration. They gel rapidly on contact with mucosal tissue, paving the way for direct nose-to-brain delivery. By circumventing first-pass metabolism in the stomach, intestines and liver, bioavailability may be dramatically improved, even compared to other nasal sprays and alternative delivery systems. The gel stays in the nasal passages, providing controlled CBD release while maintaining activity for up to seven days. Its ease of application, long-lasting effects and absence of negative side-effects may make it attractive for patients over other delivery systems.

The Company’s Development and Management Team

PreveCeutical Medical’s research team is led by Dr. Harendra Parekh, Ph.D., based at the Pharmacy Australia Centre of Excellence (PACE) at the University of Queensland. He is joined by Chief Science Officer Dr. Makarand Jawadekar, Ph.D., who has 28 years of experience in R&D with Pfizer Inc. They are supported by research collaborators, Dr. Rakesh Veedu and Professor Grant Ramm. Dr. Veedu is an emerging international expert in molecular medicine, while Professor Ramm is currently head of a leading medical research institute in Brisbane, Australia.

PreveCeutical also partners with industry experts and companies in its drive to establish a leadership position in the preventative health sciences sector. Its research and development partnership with the University of Queensland’s commercialization company, UniQuest, grants PreveCeutical rights to all intellectual property arising from projects created by the partnership.

The Company’s management team has extensive experience in research, product development, deep corporate strategy development and leadership in capital markets. PreveCeutical is re-capitalizing to fund its ambitious research and development program. Following a private placement completed in July 2017, the company expects the next round of financing to close in mid-February.

A recent Crystal Equity Research report summarizes the company’s differentiated endeavors in health care, highlighting PreveCeutical’s ability to raise the capital needed to execute its business plans.

“Our bullish view on PreveCeutical Medical is influenced by the Company’s plans to bring novel therapeutic compounds to the market at a time when the preventative health care market is entering a period of rapid growth. Management has demonstrated the ability to garner investor support and raise capital at a critical time in its development agenda, a recognized key to success for any health sciences company. Management has also been successful in securing research and development talent through a strategic relationship with a respected and successful academic institution,” reads the report (http://nnw.fm/Ho4v2).

Industry Comparables

Another innovative biotech, Lexaria Bioscience Corp. (OTC: LXRP), has developed disruptive delivery technology that facilitates healthier ingestion methods, lower overall dosing and higher effectiveness of lipophilic active molecules. The company out-licenses its delivery platform, which has multiple patents pending in more than 40 countries. Patents have been granted in the United States and Australia for the use of its DehydraTECH™ delivery technology. This provides increased intestinal absorption rates, faster delivery to the bloodstream and taste-masking benefits for orally administered cannabinoids, vitamins, non-steroidal anti-inflammatory drugs (NSAIDs), nicotine and other molecules.

London-headquartered GW Pharmaceuticals plc (NASDAQ: GWPH) focuses on discovering, developing and commercializing new therapeutics across a wide range of disease areas using its proprietary cannabinoid product platform. The company commercialized the world’s first plant-derived cannabinoid prescription drug, Sativex®, for the treatment of spasticity due to multiple sclerosis. Together with its U.S. subsidiary, Greenwich Biosciences, GW is proceeding with an orphan drug program for childhood epilepsy. It has filed a New Drug Application (NDA) with the FDA for its CBD-based drug Epidiolex for the adjunctive treatment of Lennox-Gastaut Syndrome (LGS) and Dravet Syndrome. Other products in its development pipeline include compounds in Phase 1 and 2 trials for glioblastoma, schizophrenia and epilepsy.

Canopy Growth Corp. (TSE: WEED) offers distinct brands and curated cannabis varieties in dried, oil and capsule form. The company operates seven cannabis production sites with more than 665,000 square feet of production capacity, which includes over 500,000 square feet of GMP-certified production area. It has global reach, with operations in seven countries across four continents. Canopy Growth educates healthcare practitioners and the public on cannabis. Through its partly owned subsidiary Canopy Rivers Corporation, the company builds its portfolio of stable investments by incubating new entrants to the cannabis market. Canopy Health Innovations, another partly owned subsidiary, focuses on research for commercial opportunities and IP development.

These companies are rising to the challenges presented by the increasing consumer demand for cannabis-based products. They are positioning themselves to assume leadership positions in their respective sectors of the cannabis industry to realize maximum value for their shareholders.

For more information on PreveCeutical Medical Inc., please visit: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE:18H).
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Tue Jan 30, 2018 5:35 pm

NetworkNewsBreaks – PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Details Research and Option Agreement with UniQuest Pty Limited

Health sciences company PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) this morning announced and detailed its entry into a research and option agreement with the University of Queensland (“UQ”) and UniQuest Pty Limited, UQ’s main commercialization company. Per the terms of the agreement, the parties intend to conduct a research program aimed at expanding the use of their disulfide linker technology and developing non-addictive analgesics for the treatment of pain. The research program has a targeted start date of March 1, 2018, and is expected to be led by UQ researcher and PreveCeutical Chief Research Officer Dr. Harendra Parekh. PreveCeutical will own all intellectual property developed under the program and will be granted an option to negotiate an exclusive worldwide license to UniQuest’s background IP.
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Thu Feb 01, 2018 5:41 pm

PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Teams with UniQuest to Develop Novel Cannabinoid Delivery System

- Global nasal drug delivery technology market expected to reach $64 billion by 2021
- Development of CBD-infused soluble gel for nasal delivery targets range of diseases
- Clinical benefits of Sol-gel delivery method include a safer, more reliable delivery platform with higher efficacy

Health sciences company PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) and UniQuest Pty Limited, the main commercialization company of the University of Queensland (UQ), Australia, are expecting 2018 to be an exciting, productive year for joint medical research projects. PreveCeutical Medical, headquartered in Vancouver, British Columbia, has entered into a research and option agreement with the University and UniQuest to develop a soluble gel to deliver cannabinoids directly to the brain via the nasal cavity. In a press release discussing the latest research project, UniQuest CEO Dr. Dean Moss said that PreveCeutical’s interest in the University’s intellectual property and expertise to develop soluble gels (Sol-gels) to deliver cannabinoids to the central nervous system (CNS) fit naturally with the company’s research goals (http://nnw.fm/cV6B1).

“Sol-gels potentially provide a safer, more reliable platform to deliver drugs, such as cannabinoids, directly to the CNS, avoiding unwanted rapid metabolism, thus providing clinical benefit from direct nose-to-brain delivery,” Dr. Moss said in the release.

The global nasal drug delivery technology market is projected to reach $64 billion by 2021, expanding at a compound annual growth rate of 6.5 percent, according to a report issued by MarketsandMarkets (http://nnw.fm/usd0S). While the report is segmented based on dosage form, therapeutic application, end user, system, container and region, it also states “intranasal drug delivery is one of the most preferred drug delivery routes among patients as well as healthcare providers.”

PreveCeutical’s proprietary nasal formulations will be designed as a CBD-based nose-to-brain delivery system targeting a range of indications such as pain, inflammation, seizures and neurological disorders. Dr. Harry Parekh, chief research officer for PreveCeutical, will lead the Sol-gel cannabinoid project from his base at the University’s School of Pharmacy.

The Sol-gels begin as a liquid that is sprayed into the nose, which then forms a gel as it is warmed in the nasal cavity. This effectively bypasses the stomach and intestines – eliminating first pass metabolism – and may dramatically improve bioavailability, even compared to nasal sprays and other newer delivery systems.

“This feature can potentially be exploited to deliver drugs through the nasal mucosa,” Dr. Parekh said. “The longer-term goal is to develop Sol-gels as safe, reliable delivery systems for cannabinoid extracts across a range of disease indications.”

Terms of the research program, which has a target start date of March 1, 2018, state that PreveCeutical will own all intellectual property developed under the program and will be granted an option to negotiate an exclusive worldwide license to UniQuest’s background IP.

“Increasing evidence of the clinical benefits associated with cannabinoids and the recent legalization of medical marijuana across a number of jurisdictions were the drivers for the collaboration,” Stephen Van Deventer, PreveCeutical chairman and CEO, added in a news release. “Working with UniQuest and UQ will provide the company with unique opportunities to develop new health and wellness products… Nasal delivery of cannabinoids could potentially provide a safer and more reliable delivery platform with clinical benefits for pain, inflammation, seizures, and mental illness.”

For more information, visit the company’s website at www.PreveCeutical.com
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Mon Feb 05, 2018 4:38 pm

PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Developing Alternative Solutions in Health-Boosting Market

- Company offers options to patients seeking immune system-boosting alternatives
- Novel “scorpion venom” product builds on popular Cuban cancer-fighting therapy
- Developing a CBD-based nose-to-brain delivery system that will provide relief across a range of indications from pain, inflammation, seizures and neurological disorders

In an era when a licensed and regulated medical industry provides a secure standard of care for treating ailments but “complementary” or alternative therapies are sought by a number of patients — more than three out of 10 adults, according to the National Institutes of Health’s most recent survey on the subject (http://nnw.fm/L7uE5) — PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) is offering patients novel choices in how to better the quality of their lives. PreveCeutical Medical is dedicated to proactive thinking in personal health management amid a growing market for preventive care, but, when things go wrong and clinical solutions aren’t readily available, the company also wants to help find alternatives that result from the best products nature and science can cooperatively deliver. The early-stage life sciences company has brought one product to market, a solution derived from Caribbean blue scorpion venom, and it is pursuing five other research projects under its product development program.

“We are encouraged from the fact that the Caribbean Blue Scorpion venom peptides bypasses the blood brain barrier and attaches to the abnormal cells, this is an indicator that we are going in the right direction,” PreveCeutical CEO Stephen Van Deventer stated in a news release last August (http://nnw.fm/WvCe2) announcing the company’s partnership with Sports 1 Marketing (S1M) to develop the scorpion venom as a treatment for concussions, or mild traumatic brain injury, among athletes.

The scorpion venom product builds on discoveries in Cuba and the surrounding Caribbean nations advancing the popular belief that the venom inhibits the growth of cancer cells. PreveCeutical’s product, CELLB9Ò dietary supplement, utilizes select peptides from the blue scorpion (which is actually red, with a blue tail) to boost the user’s immune system, and the company is advancing its research into producing a “nature identical” scorpion peptide solution that it hopes will be able to not only halt the progress of cancerous tumors, but also treat metabolic disorders, pain, cardiovascular disease and infectious maladies without requiring company representatives to travel to the Caribbean to find and milk the unique scorpions for their naturally produced venom.

The company is also working on a medical cannabis gel formulated drug delivery system to deliver relief from ailments such as pain, inflammation, seizures and neurological disorders via nasal administration that potentially avoids side effects that might accompany the digestion of cannabidiol through the gastrointestinal system. The proprietary “Sol-gel” research and development program is being conducted in Brisbane, Australia, and, in November, PreveCeutical received approval from the Queensland state government to acquire, store and use high-quality dried cannabis plant extracts through its partnership with UniQuest Pty Limited at the University of Queensland (http://nnw.fm/2gNFp). Once an importation permit is acquired, PreveCeutical can begin shipping cannabis from its Canadian-licensed producer.

Another initiative with a longer development schedule involves finding a therapy to treat obesity and diabetes by targeting an overactive gene common to both ailments. The company is searching for a breakthrough on non-addictive analgesics as a replacement to highly addictive analgesics such as morphine, fentanyl and oxycodone.

On January 15, PreveCeutical announced its place in the blockchain fintech revolution by accepting bitcoin as a payment option for CELLB9Ò (http://nnw.fm/Qu8bc). Despite stock fluctuations during the past month, the bitcoin cryptocurrency remains popular with individuals who conduct commerce on a global scale and who seek a seamless transaction process that doesn’t require fees or other potential obstacles that may arise from using third-party banks. PreveCeutical made the decision after receiving requests from several customers.

For more information, visit the company’s website at www.PreveCeutical.com
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Wed Feb 07, 2018 8:12 pm

Investment Opportunities in Advanced Bioengineered Drug Delivery

NetworkNewsWire Editorial Coverage: Hydrogels have been in limited commercial use for more than two decades. However, advancements in drug delivery, and thus hydrogel technology, are driving rapid growth in the global market, which is now projected to surge to over $22 billion by 2022 with a compound annual growth rate (CAGR) of 6.3 percent (http://nnw.fm/GWv2x), according to BCC Research. In what may prove to be a groundbreaking approach in this field of exponential opportunity, PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (PRVCF Profile) is engineering a unique sol-gel nose-to-brain drug delivery platform to provide clinical relief of multiple physical maladies. Other recognized companies that have embraced new methods of drug delivery and hydrogel delivery systems include Johnson & Johnson (NYSE: JNJ), Valeant Pharmaceuticals International Inc. (VRX: NYSE), UroGen Pharma Ltd. (NASDAQ: URGN) and GW Pharmaceuticals PLC (GWPH: NASDAQ).

Hydrogel Market Driven by Drug Delivery Advances

For most of modern history, pharmaceuticals have consisted of simple, fast-acting chemical compounds administered orally or by injection. However, the continual evolution of the understanding of the human body has triggered an explosion of new and potentially lifesaving treatments. These new pharmaceutical therapeutics require revolutionary new techniques of administration. The objective of modern drug delivery systems is to deploy medications intact to specifically targeted parts of the body through a medium that can control the therapy’s administration and enhance bioavailability. To achieve this goal, researchers have turned to advances in hydrogel materials, which have demonstrated efficacy in enhancing drug targeting specificity by helping medications cross the blood-brain barrier — lowering systemic drug toxicity, improving treatment absorption rates and mitigating biochemical degradation.

Hydrogels are three-dimensional molecular structures capable of absorbing large amounts of water or biological fluids. Due to their porosity and supple consistency, they closely simulate natural living tissue — more so than any other class of synthetic biomaterials. Their resemblance to living tissue opens vast opportunities for applications in biomedical arenas. Currently, hydrogels are used for manufacturing contact lenses, hygiene products, tissue engineering scaffolds and, now, drug delivery systems.

PreveCeutical’s Novel Approach

PreveCeutical Medical (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H), a preventive health sciences company initiating a broad spectrum of preventive and curative therapies, is engineering what it believes to be the world’s first nose-to-brain hydrogel platform. Following several years of research and development by PreveCeutical’s chief research officer, Dr. Harendra Parekh, Ph.D., the company’s novel sol-gel technology is designed for superior time-released delivery of cannabinoid (CBD)-based medications. Bypassing typical delivery techniques, this nasal spray formulation is meticulously engineered to rapidly gel and deliver drugs in a controlled fashion across target tissue, which in the case of nose-to-brain delivery is the olfactory mucosal epithelium within the nasal cavity.

Conventional drug delivery, whether through oral or injectable mediums, moves drugs into the bloodstream where they are then passed through the liver. The drugs are unable to directly impact the targeted area as the liver first filters then metabolizes the drugs, which also affects release times and reduces potency. In a potentially transformative technique of drug delivery, PreveCeutical’s platform circumvents the blood-brain barrier and liver through application directly onto nasal mucosal tissue. The blood-brain barrier has long challenged effective medicine delivery due to the filtering mechanism of the capillaries that carry blood to the brain and block the passage of certain substances.

PreveCeutical’s novel sol-gel drug delivery platform is designed for use in both children and adults. Once or twice daily dosing should be reduced to once or twice a week with the product. The formulation is in liquid form when it is sprayed into the nose, then rapidly turns to a gel and is retained on the nasal mucosa. Initially targeting cannabinoid delivery, sol-gels are a platform that can be applied to numerous medicines for extended release and vastly improved bioavailability.

The proprietary sol-gel formulations are anticipated to be commercially launched with licensed medical cannabis companies within 18 months and have potential for drug delivery applications far beyond cannabinoids.

Promising Pipeline

Not a one-trick-pony, PreveCeutical has already brought one product to market and is developing a diverse portfolio of research and development programs that address large market diseases. PreveCeutical Medical’s first commercial product, CELLB9®, is an oral dilute solution infused with select peptides and proteins isolated from Caribbean Blue Scorpion venom. The active ingredients in CELLB9 have been used around the world for over 25 years and have generated volumes of anecdotal reports about their efficacy. PreveCeutical’s research team is now using proprietary chemistry to generate Nature Identical™ peptides (http://nnw.fm/B9bBj) for a range of ailments. PreveCeutical and its Australian research commercialization partner, UniQuest, are currently screening these peptides for use against some of the most aggressive diseases where there exist unmet clinical needs.

In conjunction with leading Australian research centers, PreveCeutical is also pursuing dual-gene therapy research as both a preventative measure and possible treatment for type 2 diabetes and obesity. Over five years of multi-disciplinary research has generated convincing results in disease models that a single gene may be implicated in Type 2 diabetes and obesity. PreveCeutical’s gene-silencing technology would effectively turn off the genetic signal that leads to the over-production of a key protein molecule, in turn reducing blood sugar levels and preventing the body from storing excessive fat. As Dr. Parekh stated in a press release, “…gene-silencing does not represent a mere management for diabetes and obesity, it represents the potential for a bona fide cure…”

In what may be a quantum leap in addressing the critical demand for non-additive pain medications, PreveCeutical and its partner UniQuest are expanding the use of their disulphide linker technology to develop non-addictive analgesics for moderate-to-severe pain (http://nnw.fm/4TQgv). The four-phase research program will be led by Dr. Parekh and carried out in collaboration with pain and inflammation pharmacology experts at the University of Queensland.

PreveCeutical’s pain program is of considerable importance in light of America’s opioid epidemic. As the National Institute on Drug Abuse reports, prescription opioid abuse costs the United States more than $78 billion per year. The loss of life is even more devastating, with more than 115 Americans dying from opioid overdose each day (http://nnw.fm/7nExT).

Read more on PreveCeutical’s pain program in this editorial entitled, ‘Promising New Approaches in Pain Management’: http://nnw.fm/3tQ5s.

Others Leading Delivery Platforms

Recognizable household brand Johnson & Johnson (NYSE: JNJ) also has its hand in hydrogel technology. In July 2016 the company’s Johnson & Johnson Vision Care, Inc. launched its silicone hydrogel contact lens, Acuvue Vita. As noted in a press release, the design of Acuvue Vita addressed contact lens wearer discomfort by increasing hydration, thanks to “a noncoated silicone hydrogel material that maximizes and maintains hydration all month long” (http://nnw.fm/4ArJ9). In April 2017, Johnson & Johnson released Acuvue Vita for monthly wear, and provided some insight into its HydraMax technology (http://nnw.fm/Tt31U).

Valeant Pharmaceuticals (NYSE: VRX) is a multinational specialty pharmaceutical company that develops, manufactures and markets a broad range of pharmaceutical products primarily in the areas of dermatology, gastrointestinal disorders, eye health, neurology and branded generics. Through its wholly owned subsidiary, Bausch + Lomb, a leading global eye health company, Valeant Pharmaceuticals introduced an innovative bi-weekly silicone hydrogel contact lens that helps the lens maintain 95 percent of its moisture up to a full 16 hours and provides patients maximum comfort throughout the day. In another example of hydrogel efficacy, silicone hydrogel lenses allow significantly more oxygen to reach the eye than regular soft lenses.

UroGen Pharma (NASDAQ: URGN), is a clinical-stage biopharmaceutical company developing treatments to address unmet needs in the field of urology. Its RTGel™ product is a proprietary, sustained-release hydrogel-based formulation designed for potentially improving therapeutic profiles of existing drugs. BotuGel is the company’s proprietary RTGel-based formulation of Allergan Pharmaceuticals’ BOTOX® branded drug, as a potential treatment option for overactive bladder (http://nnw.fm/5nHPn).

Though not involved with hydrogels, biopharmaceutical company GW Pharmaceuticals (NASDAQ: GWPH) demonstrates the market demand and opportunity for advanced drug delivery systems. GW Pharmaceuticals develops and commercializes novel therapeutics from its proprietary cannabinoid product platform. Among the drugs in its portfolio is Sativex, a medicinal cannabis extract indicated for the relief of multiple sclerosis symptoms and the treatment of severe neuropathic-related cancer pain. For efficacious delivery of Sativex, GW also patented a metered valve pump spray device to deliver its liquid cannabis extract, in propylene glycol and ethanol, for dosing of a patient’s sublingual mucosa. Sativex oromucosal spray has been approved for use in 30 countries outside the United States.

To accommodate advances in pharmaceutical development, the practice of drug delivery has changed dramatically over the past few decades. Even greater changes are expected as innovative new therapeutics are discovered. Innovative pharmaceutical treatments require innovative methods of administration, and the companies that develop these new delivery platforms have the potential to see rapid appreciation.

For more information on PreveCeutical, visit PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H)
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Fri Feb 09, 2018 5:45 pm

NetworkNewsBreaks – PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Advancing Work on Novel Delivery for Cannabinoid Therapies

A partnership between health sciences company PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) and Australia’s UniQuest Pty Limited aimed at furthering research and development of a soluble gel is working toward a novel means of delivering cannabinoids to the central nervous system directly from the nasal cavity in order to treat pain, inflammation, seizures and neurological disorders. The partnership is taking advantage of the growing legalization of medical marijuana throughout the world amid increasing evidence of cannabinoids’ benefits. An article discussing this reads: “The global nasal drug delivery technology market is projected to reach $64 billion by 2021, expanding at a compound annual growth rate of 6.5 percent, according to a report issued by MarketsandMarkets (http://nnw.fm/usd0S). While the report is segmented based on dosage form, therapeutic application, end user, system, container and region, it also states ‘intranasal drug delivery is one of the most preferred drug delivery routes among patients as well as healthcare providers.’”
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Re: PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF)

Postby QualityStocks » Tue Feb 13, 2018 6:37 pm

NetworkNewsBreaks – PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Aims to Halt Cancerous Tumor Progression Utilizing Scorpion Venom Product

Early-stage life sciences company PreveCeutical Medical’s (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) novel “scorpion venom” product builds on popular Cuban cancer-fighting therapy. An article discussing the company’s innovative solutions reads: “The scorpion venom product builds on discoveries in Cuba and the surrounding Caribbean nations advancing the popular belief that the venom inhibits the growth of cancer cells. PreveCeutical’s product, CELLB9Ò dietary supplement, utilizes select peptides from the blue scorpion (which is actually red, with a blue tail) to boost the user’s immune system, and the company is advancing its research into producing a “nature identical” scorpion peptide solution that it hopes will be able to not only halt the progress of cancerous tumors, but also treat metabolic disorders, pain, cardiovascular disease and infectious maladies without requiring company representatives to travel to the Caribbean to find and milk the unique scorpions for their naturally produced venom.”
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