India Globalization Capital, Inc. (IGC)

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India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Mon Mar 13, 2017 4:02 pm

India Globalization Capital, Inc. (NYSE MKT: IGC) is a first mover in developing a portfolio of products using cannabis-based “combination therapies” for the treatment of pain and other conditions.

The national cost of health care due to pain ranges from $560 billion to $635 billion. In addition, the health care cost attributed to the abuse of prescription opioids, closely related to pain, is approximately $25 billion. IGC’s patent filing (IGC-501) is a cannabis-based formulation addressing neuropathic and arthritic pain in joints and muscles using a variety of delivery techniques. The Company anticipates commencing clinical trials, and hopes that through its focus on combination therapy it can formulate and commercialize cannabinoid compounds as an alternative to long-term addictive opioid treatments.

The Company has also filed combination therapy formulations for the treatment of epilepsy and cachexia. About 50 million people worldwide are affected by epilepsy and about 1.3 million in the U.S. experience cachexia associated with cancer, MS, Parkinson’s, HIV/AIDS and other progressive illnesses. Cancer-induced anorexia/cachexia is responsible for 20% of all cancer deaths. IGC-502 indicated for seizures and IGC-504 indicated for cachexia are unique combination therapies that, if proven out by clinical trials, are expected to treat medical refractory epilepsy and eating disorders respectively, with lower side effects than conventional mono therapies.

IGC’s strategy is exciting and unique in that it is aiming to become a leader in the phytocannabinoid-based combination therapy specialty pharmaceutical sector. This first mover advantage can potentially be formidable as it begins clinical trials and further builds its patent portfolio. “The development of combination therapies utilizing cannabis represents a large, unique opportunity in this emerging specialty-pharmaceutical sector. Securing FDA approval for combination therapy is believed to be significantly faster and less expensive than new drug applications. As a result, we believe that we can bring our cannabis-based pharmaceutical products to market in both an expeditious and cost-effective manner,” stated Ram Mukunda, CEO.

IGC has recently exited its legacy businesses and currently holds international investments in land and in a hotel project. An impressive and experienced team, led by Mr. Ram Mukunda, CEO, directs IGC.

Mr. Mukunda holds degrees in Electrical Engineering and Mathematics from the University of Maryland (UMD). He founded and served as Chairman and CEO of Startec Global Communications, an international telecommunications carrier focused on providing voice over Internet protocol (VOIP) services to emerging economies. Startec, the first pure play international long distance carrier, went public on NASDAQ. He has won a number of awards, including the 2013 University of Maryland International Alumnus of the year award. Mr. Mukunda serves as an Emeritus member on the Board of Visitors at the University of Maryland, School of Engineering, and has served as Council Member at Harvard’s Kennedy School of Government, Belfer Center of Science and International Affairs. Mr. Mukunda and Dr. Krishna are the originators of all the IGC patent filings.

Dr. Ranga Krishna, Senior Advisor, is a Board Certified Neurologist with a sub specialty in Epilepsy surgery. He is the Director of Neurology at the New York Community Hospital affiliated with New York Presbyterian Weil Cornell Medical College and the Director of Stroke Service at the New York Community Hospital affiliated with New York Presbyterian Weil Cornell Medical College. He is the Medical Director and Chairman of Total Neuro Care, P.C. He is CEO of International Pharma Trials, Inc., which assists U.S. pharmaceutical companies perform Phase II clinical trials. Dr. Krishna is a member of several organizations, including the American Academy of Neurology and the Medical Society of the State of New York. He is also a member of the Medical Arbitration panel for the New York State Workers’ Compensation Board and a Founding Member of the New York State Pain Society. Dr. Krishna was trained at New York’s Mount Sinai Medical Center (1991-1994) and New York University (1994-1996). Dr. Krishna and Mr. Mukunda are the originators of all the IGC patent filings.
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Re: India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Thu Mar 16, 2017 4:08 pm

Unique Cannabis-Pharma Companies Trailblazing the Medical Cannabis Industry

The cannabis industry has swiftly turned into a multi-billion dollar opportunity. In the United States, this market’s massive growth potential is being recognized as new states legalize marijuana for medical or recreational use. Industry experts forecast the U.S. cannabis market rounding $7 billion in 2016, while the annual sale of state-legal cannabis products is forecast to exceed $20 billion by 2020. Within this flourishing market, cannabis-pharma companies like India Globalization Capital (IGC) (IGC Profile), Zynerba Pharmaceuticals, Inc. (ZYNE), OWC Pharmaceutical Research Corp. (OWCP), Insys Therapeutics, Inc. (INSY) and GW Pharmaceuticals plc (GWPH) are carving lanes of unprecedented opportunities in the medical field.

Bethesda, Maryland-based India Globalization Capital (IGC) (IGC Profile) is advancing the development of cannabis-based therapies targeting large market conditions and illnesses. IGC is on a mission to treat chronic and terminal neurological and oncological diagnoses and other life altering conditions utilizing an exciting and specialized IP platform that formulates and tests combination therapies. With this special focus in mind, IGC has amassed a portfolio of patent filings covering the indications of pain, medical refractory epilepsy and cachexia (cancer-induced anorexia) using cannabinoids. As we will further discuss later, IGC has established an approach that significantly differentiates the company from its cannabis-pharma peers.

Like IGC, Zynerba Pharmaceuticals (ZYNE) is dedicated to the development of innovative cannabinoid treatments that target seizures and pain. Unlike IGC and Cannabics, this clinical-stage, specialty pharmaceutical company is concentrating on developing transdermal synthetic cannabinoid treatments. On March 13, 2017, the company announced that it had completed enrolling patients for Phase 2 of its STAR 1 (Synthetic Transdermal Cannabidiol for the Treatment of Epilepsy) clinical trial evaluating ZYN002 cannabidiol (CBD) gel in adult epilepsy patients with refractory focal seizures. Zynerba also revealed that it had completed enrollment for its Phase 2 STOP (Synthetic Transdermal Cannabidiol for the Treatment of Knee Pain due to Osteoarthritis) clinical trial evaluating ZYN002 CBD gel for the treatment of osteoarthritis.

OWC Pharmaceutical (OWCP), through its wholly owned One Word Cannabis Ltd. Israeli subsidiary, is focused on conducting medical research and pursuing clinical trials to develop cannabis-based pharmaceuticals and treatments for a variety of conditions. The company is developing two unique delivery systems to effectively dose and deliver medical cannabis. The first is a proprietary, cannabinoid-enriched sublingual tablet for the treatment of multiple myeloma, post-traumatic stress disorder, and fibromyalgia. In in-vitro testing, the tablets demonstrated 100% malignant cell death in 60% of infected mice cells. The second product is a proprietary topical compound for the treatment of psoriasis. In addition, OWC Pharmaceutical operates a Consulting Division created to help governments and companies navigate complex international cannabis regulatory frameworks.

Another industry peer, Insys Therapeutics, Inc. (INSY), is developing medications to treat addiction to opioids, opioid overdose, epilepsy and other disease areas with high unmet need. The commercial-stage company uses proprietary sublingual spray technology to develop pharmaceutical cannabinoids to address clinical shortcomings of products already on the market. Insys currently markets its FDA-approved SUBSYS® (fentanyl sublingual spray) for pain management in cancer patients who are tolerant to opioid therapy. The company has also received approval for Syndros™ for the treatment of chemotherapy-induced nausea and vomiting, as well anorexia associated with weight loss in persons with AIDS. Syndros is an orally administered liquid formulation of the pharmaceutical cannabinoid dronabinol, a pharmaceutical version of tetrahydrocannabinol (“THC”).

In terms of market share, the giant on the list of cannabis-focused biopharmaceutical companies is GW Pharmaceuticals (GWPH), which is focused on the development of plant-derived cannabinoid therapeutics based on its proprietary cannabinoid product platform. The company’s primary focus is on disorders of the central nervous system (CNS). Within this arena, GW’s lead cannabinoid product candidate is Epidiolex® (cannabidiol), in development for the treatment of rare childhood-onset epilepsy disorders. The company’s Sativex® (nabiximols) prescription drug, a therapy approved for the treatment of spasticity due to multiple sclerosis, is the world’s first plant-derived cannabinoid prescription drug. Additionally, GW boasts a deep pipeline of additional cannabinoid product candidates which includes clinical-stage compounds for glioma, schizophrenia and epilepsy.

It’s an impressive and interesting lineup, but what sets India Globalization Capital (IGC) (IGC Profile) apart from the other players is its foray into the larger market for cannabis-based combination therapies that would treat pain and other conditions. The company recently filed patents (http://nnw.fm/ggBB6) for formulations that will reduce the side effects of single drugs by being combined with a cannabinoid. IGC filed IGC-501 for a cannabis-based formulation to treat neuropathic and arthritic pain in joints and muscles using a variety of delivery techniques.

India Globalization Capital also filed combination therapy formulations for the treatment of epilepsy/seizures (IGC-502) and cachexia (IGC-504). IGC-501, IGC-502 and IGC-503 are novel combination therapies that, if proven out by clinical trials, are expected to treat pain, medical refractory epilepsy and eating disorders respectively, with lower side effects than conventional therapies.

Such “combination therapies” have the unique opportunity to quickly move through the FDA’s approval process, since the drugs have already been individually approved. Consequently, IGC believes it has “first mover” advantage in pursuing this approach to bring cannabis-based pharmaceutical products to market in a quick and cost-effective manner.

The cannabis industry is growing in popularity. The wave of enthusiasm surrounding the recent legalization of cannabis in several new states is sweeping the country and IGC anticipates an explosion in demand for cannabinoid-based pharmaceutical therapies, technology, facilities and financial services. With a solid strategic plan in hand, this NYSE MKT listed company has a modest $9 million market capitalization which is just a fraction of their peer group, and is aggressively leaning on its connections to medical and procedural expertise to take advantage of one of many ground-floor opportunities. And, it is developing innovative therapies, while also acquiring technologies from related industries that will place it in the right position for capitalizing on its first-mover advantage.

For more information on India Globalization Capital (IGC) please visit India Global Capital (IGC) or http://www.igcinc.us
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Re: India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Tue Mar 21, 2017 6:11 pm

India Globalization Capital, Inc. (NYSE: IGC) Pioneering New Phytocannabinoid Products

Although legal in 28 states for medicinal use, cannabis is still considered a dangerous substance in much of the country. However, many experts now believe that cannabis is a safe alternative to pharmaceuticals for relieving symptoms related to multiple illnesses. Scientific research shows that phytocannabinoids, cannabinoids that occur naturally in the cannabis plant, are effective at relieving convulsions, seizures, anxiety, nausea, and inflammation. From fighting glaucoma to controlling epileptic seizures and easing pain, scientific research has repeatedly shown the efficacy of medicinal marijuana.

Due to government misclassification of cannabis as a Schedule 1 drug, there has been only marginal progress in the utilization of phytocannabinoids, which hold such promise in disease treatment and pain mitigation. Although many pharmaceutical companies still avoid association with cannabinoids, attitudes are changing, and the medicinal benefits of marijuana are being recognized for their worth.

With changes in the acceptance of medicinal marijuana, some pharmaceutical companies are finally beginning to unpack the myriad of potential benefits phytocannabinoids hold. India Globalization Capital, Inc. (NYSE MKT: IGC) is pioneering such efforts. A multi-faceted company with global experience, India Globalization has a primary focus on developing novel cannabis-based therapies for the treatment of debilitating or life threatening conditions. The company’s current pipeline of patented drugs is focused on large market maladies, including therapeutics for neuropathic pain, human and animal seizures, refractory epilepsy, and eating disorders. Several of the company’s products are scheduled for pre-clinical trials this year.

A transformation is now underway in the medical use of cannabinoids for disease treatment, and India Globalization “believe(s) that the legalization of the cannabis industry will create an explosion in demand for cannabinoid-based pharmaceutical therapies, technology, facilities, and financial services.” With a patent portfolio of cannabinoid-based therapies, the company is well positioned for the quickly arriving time when medical cannabis gains widespread acceptance.

For more information, visit the company’s website at www.IGCinc.us
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Re: India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Tue Mar 28, 2017 5:09 pm

India Globalization Capital, Inc. (NYSE: IGC) Aims to Become a Leading Provider of Cannabis-Based Combination Therapies

India Globalization Capital, Inc. (NYSE MKT: IGC) has set a long-term goal for itself in the U.S. of becoming a leading provider of cannabis-based pharmaceutical and nutraceutical products. This is a transition away from its earlier short-term strategy, including the sale of electronics and development of a hotel site in Malaysia. To this end, the company has jettisoned its electronics business. IGC is now fully focused on building a portfolio of patents and starting clinical and pre-clinical trials for a series of pain-reducing and other cannabis-based therapies. These therapies are designed to treat neuropathic pain, seizures, Parkinson’s, anorexia/cachexia, Alzheimer’s, and PTSD.

Ram Mukunda, CEO of the company, indicated that IGC’s 2017 goals are focused on its progression toward commencement of clinical trials for these combination therapies. The Journal of Pain, in September 2012, reported that between $560 billion and $635 billion is spent annually in the U.S. for pain management, making it a significant part of the American health care system. In response, IGC has developed a series of drugs for pain and other disorders, including IGC-501 for neuropathic pain, IGC-502 for the treatment of seizures, and IGC-504 and IGC-506 for eating disorders and cachexia.

The company recently filed for issuance of a provisional patent for IGC-506, a combination of cannabis-based extracts and other compounds. It should be noted that a provisional patent does not assure the issuance of a patent in the future.

Mukunda explained that IGC is starting a review of international medical sites as the company seeks preclinical and clinical trials of its patent portfolio. He described the marketplace that IGC is entering as large, indicating that trials, patents and seeking approval from the U.S. Food & Drug Administration is seen as cost-effective.

For more information, visit the company’s website at www.IGCinc.us
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Re: India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Thu Mar 30, 2017 4:36 pm

Pain-Reducing Combination Therapies Proving Successful thanks to Innovative, Specialty Pharma Players

Combination therapies that use cannabis-based pain reduction methods without the negative side effects of opioids are looking to be a positive growth opportunity among specialty pharmaceuticals, particularly for postoperative and chronic pain relief. Leading specialty pharma companies such as India Globalization Capital, Inc. (NYSE: IGC) (IGC Profile), Cara Therapeutics, Inc. (NASDAQ: CARA), Zynerba Pharmaceuticals, Inc. (NASDAQ: ZYNE), and INSYS Therapeutics, Inc. (NASDAQ: INSY) are tirelessly working to expand combination therapeutics product lines, while Pacira Pharmaceuticals, Inc. (NASDAQ: PCRX) developing an opioid alternative drug intended to reduce pain after surgery.

To date, it is estimated that the annual national cost of pain is between $560 billion and $635 billion – more than priority health conditions among the nation. Sadly, the treatment of postoperative pain remains a daunting challenge for health care professionals, leaving patients debilitated in ways that can affect their daily functioning and, in turn, have a significant impact on our nation’s overall productivity. At present, patients face a significant disadvantage when using opioid drugs to treat postoperative and chronic severe pain, and usage thereof can lead to impactful side effects such as nausea, hallucinations, respiratory depression, constipation, and sedation.

While opioids have been widely accepted as a standard therapy to treat acute post-operative pain, the frequent adverse effects and burden of the cost of care has proven to be a barrier for patients who are unable to receive optimal dosing or adhered to their prescribed treatment. The administration of two opioids is not usually recommended as a treatment for moderate to severe acute pain; however, cannabis-based combination therapies present a unique opportunity in the health sector. Cannabis pharma company India Globalization Capital (IGC) has carved an impressive course in the combination therapy market as a “first mover” to combine existing drugs with cannabis. IGC recently filed a patent for a formulation that the company claims will reduce the side effects of single drugs by combining them with a cannabinoid. In particular, IGC has filed for a provisional patent for the treatment of several eating disorders that uses a combination of compounds and cannabis extracts. The combo therapy is ear-marked for both veterinary and human consumption.

After three years of building a sturdy IP portfolio, IGC is now set to obtain funding to begin both pre-clinical and clinical trials for combination therapies, for which it has started reviewing international medical facilities. Fortunately, securing FDA approval for such therapies, which include the treatment of seizures, neuropathic pain and eating disorders, tends to be swifter and less costly than applying for new drug approval. It is the company’s aim to leverage its unique first-mover position and bring its cannabis-based pharmaceuticals to market in a cost-effective and prompt manner.

Meanwhile, Pacira Pharmaceuticals (PCRX), which is collaborating with Trinity Health to develop an alternative approach to opioids for pain management, recently announced positive results for its medication for opioid reduction in a phase 4 clinical trial. During the trial, a pain regimen along with EXPAREL® was tested against a bupivacaine-based pain regimen that involved other drugs in 139 patients who were undergoing knee replacements. EXPAREL, currently used to produce postsurgical analgesia, combines bupivacaine with the DepoFoam® platform to enable the delivery of bupivacaine over a desired period of time, providing significant reductions in pain with up to a 45 percent decrease in opioid consumption.

In the phase 4 clinical trial, EXPAREL achieved statistical significance for its co-primary endpoints for postsurgical pain and opioid reduction, as well as achieved statistical significance for key secondary endpoints. In a press release announcing the results, Pacira said it continues to analyze further secondary endpoints.

Cara Therapeutics (CARA) is also working to change pain management on a fundamental level. Rather than concentrating on improving old compounds, the company is developing a new class of medicine referred to as KORAs – Kappa Opioid Receptor Agonists. This medication is aimed at targeting different receptors in the body to treat pain in an unconventional, yet more effective, manner. Up to now, Cara’s core product has shown favorable results in phase 2 clinical trials for pain relief and does not elicit the usual side effects patients would normally experience when using opioids such as hydrocodone, morphine, and non-steroidal anti-inflammatories.

Two more candidates for combination therapies come from Zynerba Pharmaceuticals (ZYNE). ZYN001 and ZYN002 are both being evaluated in various therapeutic indications at the moment. ZYN001, a pro-drug patch that comprises of THC, is aimed at enabling transdermal delivery via a person’s skin and into their circulatory system. ZYN002, a CBD gel, is the first of its kind and is designed to act as a non-psychoactive cannabinoid. The gel is to be delivered via the skin and absorbed into a patient’s circulatory system. At present, the gel is in phase 2 of clinical development with patients who suffer with osteoarthritis of the knee, refractory epilepsy, and Fragile X Syndrome.

Focused on the development and commercialization of innovative therapies that improve the quality of life of patients, Insys Therapeutics (INSY) is developing a pipeline of products intending to address unmet medical needs and clinical shortcomings of existing commercial products. The Drug Enforcement Agency recently issued a provisional final ruling that is to result in Insys’ SYNDROS™ being placed in Schedule II of the Controlled Substances Act. The product has been designed for chemotherapy patients and is aimed at helping to alleviate vomiting and nausea. It is also aimed at helping AIDS patients suffering from anorexia-type weight loss.

To date, there are some 53 million outpatients and 45 million inpatient surgeries that are performed in the United States annually. These surgeries necessitate drugs for postoperative pain, and more than half of postoperative patients continue to experience poor pain relief. At present, the therapeutic classes for postoperative pain management involve analgesics such as hydromorphone, morphine, and fentanyl, as well as NSAIDs – non-steroidal anti-inflammatories. Furthermore, the market is awash with injectable opioids that are administered either via epidural, intravenous, intrathecal, or intramuscular. Usually, the injections are administered either by patient-controlled analgesia devices or hospital personnel.

It has been found that the market for effective acute pain management in the form of combined therapies outside of the hospital setting exceeds more than 200 million prescriptions yearly. While products such as opioid analgesic combinations make up the bulk of the market, the products have significant side-effects, including sedations, dizziness, respiratory problems, substance abuse, euphoria, vomiting, and nausea. Hence, there is a vast market for combined therapies that are able to manage acute pain without producing the negative and uncomfortable side effects.

For more information on India Globalization Capital please visit India Global Capital (IGC)
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Re: India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Fri Mar 31, 2017 5:04 pm

India Globalization Capital, Inc. (NYSE: IGC) From Mining to Marijuana

At first blush, India Globalization Capital (NYSE: IGC) would seem a curiosity clothed in an enigma. Just how does a NYSE company move from a successful mining orientation to a pioneer in the development of multiple cannabinoid-based pharmaceutical therapies to treat pain and disease? The enigma can be disrobed by looking at the tenacity and vision of its management.

Ram Mukunda has served as Executive Chairman, CEO and President of India Global since inception in 2005. He holds distinguished mathematics and engineering degrees and worked in multiple Wall Street positions for more than 25 years, serving communications firms such as Intelsat SA and Startec. Mukunda actually founded Startec in 1991 to provide VOIP service to emerging economies. As Chairman and CEO of Startec, he led the company to a $60 million public stock offering in 1997. His introduction to the mining industry came a few years later through a company he co-founded, India Globalization Capital. The company mined and converted low-grade iron ore to high-grade ore. Iron ore prices subsequently plummeted nearly 75 percent, putting it below the cost of production. That’s when Mukunda made a difficult decision and charted a course change for the company.

Realizing that the lucrative mining business was bust, he searched for a growth arena to position the company and move forward. He ultimately centered on the burgeoning cannabis industry and the myriad of potential medical benefits. Mukunda and his team realized that there were a lot of untapped uses for cannabinoids and cannabis-based extracts. They recruited a team of highly skilled doctors and patent attorneys, comparing anecdotal stories with scientific evidence and identifying areas where patents had not been filed. This process has yielded results.

The company now has a pipeline of patent pending cannabinoid-based drugs targeting large market maladies, which includes therapeutics for neuropathic pain, human and animal seizures, refractory epilepsy and eating disorders. Several of these therapeutic drugs are scheduled for pre-clinical trials this year. The company is transitioning fast from building research teams and developing a patent portfolio to marketable products.

For the past few years, India Globalization Capital has also focused interest on cannabis-based combination therapies, using cannabis-based extracts in combination with other medications to reduce side effects and increase bioavailability and absorption. As one of the first to enter this space, the company has been building intellectual property around these precepts and expects to reap substantial rewards from this arena.

From mining to medical marijuana would seem an incredible leap, but, when looking at India Global and the leadership of Ram Mukunda, it would be tough to bet against a leader with such tenacity and vision. And with a $12MM market cap, IGC is quite compelling given the valuations attributed to its peers.

For more information, visit the company’s website at www.IGCinc.us
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Re: India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Fri Apr 07, 2017 3:43 pm

India Globalization Capital, Inc. (NYSE: IGC) at the Forefront of Innovation Thanks to Strategic Alliances

How does a company in the mining industry successfully move toward becoming a leader in the marijuana sector, specifically cannabinoid-based pharmaceutical therapies that treat a variety of diseases and conditions? In the case of India Globalization Capital, Inc. (NYSE MKT: IGC), the answer is creative management’s ability to identify opportunity, coupled with a relentless drive toward innovation.

IGC made its switch to the marijuana industry after its CEO, Executive Chairman, and President Ram Mukunda was unafraid to recognize and act on a need for the company to make a positive and swift switch to a stronger and more lucrative market. This led IGC to cannabis and, in particular, phytocannabinoids.

The cannabis plant has a number of subspecies, some of which have psychoactive properties and others do not. Cannabis sativa is psychoactive, while other forms, such as Cannabis Sativa L., or hemp, and Cannabis ruderalis, are not. In fact, the latter offer high levels of cannabidiol, which is most commonly used on a medical level.

Legal marijuana is now becoming one of the fastest growing industries in the United States, expected to create just under 300,000 jobs for Americans by 2020 (http://nnw.fm/xM4lJ), and an increasing number of states are legalizing the drug both medically and recreationally, with the potential for further legalization on the horizon.

Although the marijuana industry is growing at an exponential rate, federal laws that classify marijuana as a Schedule 1 drug make it hard for businesses to reach their full potential,but IGC has been able to research and take advantage of cannabinoids, since these are not illegal. Part of IGC’s success is due to the fact that the company is not going about its mission to help patients suffering from pain, PTSD, seizures, and many other diseases on its own. The company is creating strategic alliances with doctors, researchers, dispensaries, and practitioners, among other industry experts, in order to develop a product portfolio of much needed phytocannabinoid-based therapies.

IGC has entered into the industry aware that there is a huge amount of information already available at the grassroots level of the marijuana industry. This is why it is seeking IP transfers with producers who know about growing hybrids and strains that are rich in specific phytocannabinoids that can be used in a pharmaceutical environment to help patients who could benefit from cannabinoids.

In addition to its extensive development pipeline, which includes six products for various disorders in both adults and animals and three expected to go through to preclinical trials this year, IGC is planning on taking equity positions within companies that are directly and indirectly part of the marijuana industry, another way that investors can take advantage of a booming industry.

For more information, visit the company’s website at www.IGCinc.us
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Re: India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Thu Apr 13, 2017 4:39 pm

India Globalization Capital, Inc. (NYSE: IGC) Plans to Develop Cannabinoid Extract Therapies for Cats and Dogs

India Globalization Capital, Inc. (NYSE MKT: IGC) intends to become a “first-mover” in developing cannabis-based combination therapies for large market conditions such as pain, eating disorders, refractory epilepsy, and seizures. In addition, IGC has filed two patents, IGC-502 and IGC-505, for combination therapies for the treatment of seizures in dogs and cats, which in it itself is a surprisingly large market.

It is believed that abnormal brain activity is the cause of most seizures in dogs and cats. These seizures can be either violent or subtle. Some seizures may occur just once, but others can be repeated and require treatment before affecting larger parts of the brain.

The pet market is large and growing. According to research by the American Pet Products Association (http://nnw.fm/0Wi4y), the market in 2017 is expected to reach $16.62 billion for veterinary care and $14.93 billion for supplies and over-the-counter medicine. By far, dogs and cats are the most popular pets. In a 2017 survey by National Pet Owners, 60.2 million American households owned a dog and 47.1 million households owned a cat.

While some of this research may also be beneficial for treating humans, it reflects IGC’s targeting of the larger veterinary market. In dogs, primary epilepsy — or idiopathic epilepsy — occurs in about 5% of the canine population (http://nnw.fm/6LTia), most often in dogs between the ages of six months and six years. In cats, seizures are much less common, occurring in only 0.5-1.0% of the population. Most are intracranial, stemming from the brain, and are epileptic in nature.

Hemp-based products for dogs, especially for older and pain-ridden dogs, are in a gray market. However, the market potential is great (http://nnw.fm/4iNu8), because it sits at the current intersection of medical pharmaceutical marijuana and pet care. Veterinarians acknowledge that legal restrictions currently impede distribution of these products in the U.S., but advances in legalization of medical marijuana may be helpful in changing the environment. For now, IGC is researching the potential of cannabis-based treatments in the pet market and developing products as this potentially represents a significant future opportunity.

For more information, visit the company’s website at www.IGCinc.us
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Re: India Globalization Capital, Inc. (IGC)

Postby QualityStocks » Mon Apr 24, 2017 3:46 pm

India Globalization Capital, Inc. (NYSE: IGC) is a First Mover in Cannabinoid Combination Therapies

The success of the Walkman back in the 1980s is testament to the power of getting to market first. By some accounts, Sony sold over 200 million units of its innovative portable cassette player (http://nnw.fm/H6spU). Now, India Globalization Capital, Inc. (NYSE MKT: IGC) is taking a leaf from the Sony playbook. This pioneering company is a ‘first mover’ in the cannabinoid combination therapy space. IGC is developing a portfolio of products that use cannabinoids in conjunction with existing drugs to tackle chronic pain and a variety of other debilitating medical conditions.

Chronic pain from a range of ailments plagues millions around the world, and many of the analgesics employed to treat it, such as morphine, codeine, and hydrocodone, are opioids. However, opioids are notoriously addictive and their use is often subverted from pain relief. Used as recreational drugs, ‘opioid addiction is America’s 50-state epidemic’, the New York Times has reported (http://nnw.fm/8UBpU), with an effect that is fatal in many instances. According to the Centers for Disease Control (CDC), 29,000 Americans die every year from opioid-related overdoses. In light of these frightening developments, there is a growing imperative for less addictive anodynes.

The time is right. Results, published on Monday, April 17, of a Yahoo/Marist poll (http://nnw.fm/5BvcE) show that the public is not only becoming more apprehensive about opioids, but is warming to the use of cannabinoids to treat pain. ‘Two-thirds of the respondents in the telephone survey said opioid drugs such as Vicodin or OxyContin are “riskier” to use than pot, even when the pain pills are prescribed by a doctor.’ They will be happy to hear that IGC is coming to the rescue. The company has filed a patent for IGC-501, a cannabis-based formulation that addresses neuropathic and arthritic pain in joints and muscles using a variety of delivery techniques. IGC expects to begin pre-clinical trials for IGC-501 this year. Since approximately 80 percent of the global opioid supply is consumed in the United States, this presents a domestic market opportunity estimated at about $25 billion.

IGC-501, with its potential to replace treacherously addictive opioids, is not all that IGC has up its sleeve. The company has a robust portfolio of five other combination drug candidates with both human and veterinary applications. It has filed two patents, IGC-502 and IGC-505, for the treatment of seizures in dogs and cats. Most animal seizures stem from epilepsy, which is more common in dogs and cats than formerly recognized. About five percent of dogs and about one percent of cats are epileptic.

It also has IGC-503, aimed at refractory epilepsy, a term that’s used to describe cases of epilepsy that are unresponsive to current medications. Refractory epilepsy affects about 50 million in the U.S. alone. In the pipeline as well is IGC-504, intended for those who suffer from cachexia, known as wasting syndrome. About 1.3 million in the U.S. experience cachexia associated with cancer, multiple sclerosis (MS), Parkinson’s, HIV/AIDS and other devastating maladies. In addition, there is IGC-506, designed to combat eating disorders, which are said to affect about 30 million Americans (http://nnw.fm/v3LfJ).

IGC is out to save the world, it seems. Earlier this month, the company announced it had filed patent applications for IGC-501 in Canada, Israel and Europe in support of its ongoing cannabis-based combination therapy development initiatives.

“In 2017, our goal is to accelerate the development of our cannabis-based therapy portfolio to support key indications such as pain, seizures, cachexia, PTSD, and depression. In tandem, we expect to initiate pre-clinical trials on IGC-501-pain, IGC-502-seizures and IGC-504-cachexia,” CEO Ram Mukunda stated in a news release.

That is welcome news to the many millions who suffer daily from these conditions.

For more information, visit the company’s website at www.IGCinc.us
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